Evidence map›Paper›PMID 39718655›Full record

ArticleBrain structure & function2024

Motor predictors of cortical brain development and full-IQ in children born extremely preterm with and without discrete white matter abnormalities.

L Fernández de Gamarra-Oca, D Nosko, H Kvanta, L Broström, M Strindberg, J Svoboda, N Canto Moreira, N Ojeda, L Zubiaurre-Elorza, M Örtqvist and 2 more

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Article in Brain structure & function, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

L Fernández de Gamarra-OcaDepartment of Psychology, Faculty of Health Sciences, University of Deusto, Bilbao, Bizkaia, Spain. lexuri.fernandez@deusto.es.ORCID http://orcid.org/0000-0003-1593-6787
D NoskoDepartment of Paediatrics, Örebro University Hospital, Örebro, Sweden.
H KvantaDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
L BroströmDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
M StrindbergDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
J SvobodaDepartment of Neuroradiology, Karolinska University Hospital, Stockholm, Sweden.
N Canto MoreiraDepartment of Neuroradiology, Karolinska University Hospital, Stockholm, Sweden.
N OjedaDepartment of Psychology, Faculty of Health Sciences, University of Deusto, Bilbao, Bizkaia, Spain.
L Zubiaurre-ElorzaDepartment of Psychology, Faculty of Health Sciences, University of Deusto, Bilbao, Bizkaia, Spain.
M ÖrtqvistDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
N PadillaDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
U ÅdénDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

Funding

Department of Education of the Basque Government PRE_2019_1_0105Regional Agreement on Medical Training and Clinical Research ALF SLL 20170243Swedish Brain Foundation FO2019-0045Swedish Medical Research Council 2017-03043
6 · The paper itself

Abstract

aimTo describe the cortical brain development and full-IQ performance in middle school age children after extremely preterm (EPT) birth considering discrete white matter abnormalities (WMA). In addition, to assess possible early motor predictors of cortical brain development and full-IQ in children born EPT with and without discrete WMA diagnosed at 10 years.

methodsT1-weighted MRI images from fifty-one children born before 27 weeks' gestation and 40 full-term born controls (M

resultsNo differences were displayed in motor function or full-IQ score between children born EPT with and without discrete WMA at 10 years. Moreover, no global differences were found in cortex volume. However, bilateral mean cortical thicknesses (CTh) were exhibited to be thicker in children born EPT with discrete WMA. Children born EPT with discrete WMA exhibited regional increases mainly in the frontal and temporal lobes apart from left caudal anterior cingulate gyrus (mean difference = -0.11 (-0.22, -0.01), p = 0.026). Full-IQ was predicted by impairments in fine motor skills in children born EPT with discrete WMA, explaining 42.9% of the variance.

conclusionsBilateral mean and regional CTh were found to be greater in children born EPT with discrete WMA at 10 years compared to those without. Fine motor function at 2½ years was a strong predictor of full-IQ dependent in children with discrete WMA.

Indexed as

Infant, Extremely PrematureIntelligenceMagnetic Resonance ImagingWhite MatterCerebral CortexChildChild DevelopmentChild, PreschoolFemaleHumansInfant, NewbornMaleMotor SkillsCortical thicknessDiscrete white matter abnormalitiesExtremely preterm birthMotor function and full-IQ

Identifiers

PMID39718655

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.