Evidence map›Paper›PMID 39718554›Full record

ArticleInternational journal of STD & AIDS2025

Doxycycline post-exposure prophylaxis for preventing bacterial sexually transmitted infections (STIs): Are clinical providers supportive?

Esma Imerlishvili, John Lake, Sara Todorovic, Charles Gonzalez, Elizabeth M Boos, Rachel Hart-Malloy

Abstract read
In one paragraph

Article in International journal of STD & AIDS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Perceptions of DoxyPEP use Among Racial & Ethnic Minority Patients.Journal of racial and ethnic health disparities · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Esma ImerlishviliNew York State Department of Health AIDS Institute, Albany, NY, USA.ORCID 0000-0002-8512-0575
John LakeNew York State Department of Health AIDS Institute, Albany, NY, USA.ORCID 0009-0008-5820-3886
Sara TodorovicNew York State Department of Health AIDS Institute, Albany, NY, USA.ORCID 0009-0000-6090-8238
Charles GonzalezNew York State Department of Health AIDS Institute, Albany, NY, USA.
Elizabeth M BoosNew York State Department of Health AIDS Institute, Albany, NY, USA.
Rachel Hart-MalloyNew York State Department of Health AIDS Institute, Albany, NY, USA.ORCID 0000-0001-8114-7626

Funding

Vascular contributions to cognitive impairments and dementia (VCID) among people living with HIV in the country of GeorgiaD43TW011532 · FIC · PARTNERSHIP FOR RESEARCH/ACTION/HEALTH · PI DEHOVITZ, JACK A, DJIBUTI, MAMUKA · 2020 to 2024
$1.8M
CDC Cooperative Agreement 1NU62PS924546Centers for Disease Control and Prevention (CDC) NO.6 MH25PS005175-01FIC NIH HHS D43 TW011532
6 · The paper itself

Abstract

backgroundBacterial sexually transmitted infections (STIs) continue to increase in the United States. Despite evidence of the effectiveness of doxycycline post-exposure prophylaxis (Doxy-PEP) to prevent STIs, little is known about providers' attitudes and willingness to implement Doxy-PEP.

methodsAn online questionnaire was sent to 575 clinical providers in New York State in September 2022.

resultsNinety-one eligible individuals responded. Most providers served men who have sex with men (MSM) (84%); reported willingness to recommend Doxy-PEP (98%, 77%, and 67% for chlamydia, syphilis, and gonorrhea, respectively); preferred Doxy-PEP administration for MSM and transgender populations; believed recurring bacterial STIs (88%) and reported condomless sex (85%) were the most important characteristics to consider for recommending Doxy-PEP; and were concerned about antibiotic resistance (90%) (primarily for

conclusionsStudy results suggest high willingness and support for implementing Doxy-PEP. As this survey was administered prior to national guidelines on the use of Doxy-PEP, these data can be used as a baseline to compare to studies conducted after their release to formulate appropriate messages for providers to improve implementation.

Indexed as

Anti-Bacterial AgentsAttitude of Health PersonnelDoxycyclineHealth PersonnelPost-Exposure ProphylaxisSexually Transmitted DiseasesSexually Transmitted Diseases, BacterialAdultFemaleGonorrheaHomosexuality, MaleHumansMaleMiddle AgedNew YorkSurveys and QuestionnairesAnti-Bacterial AgentsDoxycyclinebacterial STIsDoxycycline prophylaxispost-exposure prophylaxis

Identifiers

PMID39718554
PMCPMC11993814

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.