Evidence map›Paper›PMID 39717850›Full record

ArticleToxicology reports2024

Pro-apoptotic and anti-proliferative activities of cassane diterpenoids on squamous carcinoma cells: An in vitro and in silico study.

Kelly Oriakhi, Osayemwenre Erharuyi, Kissinger O Orumwensodia, Emmanuel E Essien, Abiodun Falodun, Patrick O Uadia, Frerich Bernhard, Nadja Engel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kelly OriakhiDepartment of Medical Biochemistry, School of Basic Medical Sciences, College of Medical Sciences, University of Benin, Nigeria.
Osayemwenre ErharuyiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, Nigeria.
Kissinger O OrumwensodiaDepartment of Biochemistry, Faculty of Life Sciences, University of Benin, Nigeria.
Emmanuel E EssienDepartment of Chemistry, University of Uyo, Akwa Ibom State, Nigeria.
Abiodun FalodunDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, Nigeria.
Patrick O UadiaDepartment of Biochemistry, Faculty of Life Sciences, University of Benin, Nigeria.
Frerich BernhardDepartment of Oral and Maxillofacial Surgery, Facial Plastic Surgery, Rostock University, Medical Center, Schillingallee 35, Rostock 18057, Germany.
Nadja EngelDepartment of Oral and Maxillofacial Surgery, Facial Plastic Surgery, Rostock University, Medical Center, Schillingallee 35, Rostock 18057, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Squamous carcinoma of the head and neck is characterized by aberrant apoptosis that prolongs the proliferative capacity of the cells and by uncontrolled cell growth. This study aimed to examine the pro-apoptotic and antiproliferative effects of

Indexed as

ApoptosisCaesalpinia pulcherrimaCancerCassane DiterpenoidsCell cycleSquamous Carcinoma

Identifiers

PMID39717850
PMCPMC11665704

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.