Evidence map›Paper›PMID 39717675›Full record

ArticleDialogues in health2024

The association of combinations of social factors and SARs-CoV-2 infection: A retrospective population-based cohort study in Ontario, 2020-2021.

Sydney Persaud, Michael Fitzgerald, Steven Hawken, Peter Tanuseputro, Lisa Boucher, William Petrcich, Martin Wellman, Colleen Webber, Esther Shoemaker, Robin Ducharme and 18 more

Abstract read
In one paragraph

Article in Dialogues in health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Sydney PersaudBruyère Health Research Institute, Ottawa, Ontario, Canada.
Michael FitzgeraldBruyère Health Research Institute, Ottawa, Ontario, Canada.
Steven HawkenICES, Ottawa, Ontario, Canada.
Peter TanuseputroBruyère Health Research Institute, Ottawa, Ontario, Canada.
Lisa BoucherBruyère Health Research Institute, Ottawa, Ontario, Canada.
William PetrcichICES, Ottawa, Ontario, Canada.
Martin WellmanICES, Ottawa, Ontario, Canada.
Colleen WebberBruyère Health Research Institute, Ottawa, Ontario, Canada.
Esther ShoemakerBruyère Health Research Institute, Ottawa, Ontario, Canada.
Robin DucharmeOttawa Hospital Research Institute, Ottawa, Ontario, Canada.
Simone DahrougeBruyère Health Research Institute, Ottawa, Ontario, Canada.
Daniel MyranBruyère Health Research Institute, Ottawa, Ontario, Canada.
Ahmed M BayoumiInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
Susitha WanigaratneICES, Ottawa, Ontario, Canada.
Gary BlochDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
David PonkaBruyère Health Research Institute, Ottawa, Ontario, Canada.
Brendan T SmithDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Aisha LoftersICES, Ottawa, Ontario, Canada.
Austin ZygmuntDepartment of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Krystal Kehoe MacLeodBruyère Health Research Institute, Ottawa, Ontario, Canada.
Luke A TurcotteDepartment of Health Sciences, Brock University, St. Catharines, Ontario, Canada.
Beate SanderICES, Ottawa, Ontario, Canada.
Michelle HowardDepartment of Family Medicine, McMaster University, Hamilton, Ontario, Canada.
Sarah FunnellFaculty of Health Sciences, Queen's University, Kingston, Ontario, Canada.
Jennifer RaynerInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
Kurtis KitagawaBruyère Health Research Institute, Ottawa, Ontario, Canada.
Sureya IbrahimCentre for Community Learning & Development, Toronto, Ontario M5A 2B3, Canada.
Claire E KendallBruyère Health Research Institute, Ottawa, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The COVID-19 pandemic highlighted and exacerbated health inequities worldwide. While several studies have examined the impact of individual social factors on COVID infection, our objective was to examine how interactions of social factors were associated with the risk of testing positive for SARS-CoV-2 during the first two years of the pandemic. Study design and setting: We conducted an observational cohort study using linked health administrative data for Ontarians tested for SARS-CoV-2 between January 1st, 2020, and December 31st, 2021. We constructed multivariable models to examine the association between SARS-CoV-2 positivity and key variables including immigration status (immigrants vs. other Ontarians), and neighbourhood variables for household size, income, essential worker status, and visible minority status. We report main and interaction effects using odds ratios and predicted probabilities, with age and sex controlled in all models. Results: Of 6,575,523 Ontarians in the cohort, 88.5 % tested negative, and 11.5 % tested positive for SARS-CoV-2. In all models, immigrants and those living in neighbourhoods with large average household sizes had greater odds of testing positive for SARS-CoV-2. The strength of these associations increased with increasing levels of neighbourhood marginalization for income, essential worker proportion and visible minority proportion. We observed little change in the probability of testing positive across neighbourhood income quintiles among other Ontarians who live in neighbourhoods with smaller households, but a large change in probability among other Ontarians who live in neighbourhoods with larger households. Conclusion: Our study found that SARS-CoV-2 positivity was greater among people with certain combinations of social factors, but in all cases the probability of testing positive was consistently greater for immigrants than for other Ontarians. Examining interactions of social factors can provide a more nuanced and more comprehensive understanding of health inequity than examining factors separately.

Indexed as

COVID-19 positivityHealth equitySARS-CoV-2Social determinants of health

Identifiers

PMID39717675
PMCPMC11664076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.