Evidence map›Paper›PMID 39717327›Full record

ArticleCureus2024

A Three-Year Analysis of Mortality in Clostridioides difficile Patients in a Tertiary Center.

George S Gherlan, Simin Aysel Florescu, Mihaly Enyedi, Ion Cristian Efrem, Adina Mitrea, Diana Clenciu, Stefan D Lazar

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

George S GherlanInfectious Diseases, Clinic Hospital of Tropical and Infection Diseases "Dr. Victor Babes", Bucharest, ROU.
Simin Aysel FlorescuInfectious Diseases, Clinic Hospital of Tropical and Infection Diseases "Dr. Victor Babes", Bucharest, ROU.
Mihaly EnyediAnatomy, University of Medicine and Pharmacy "Carol Davila", Bucharest, ROU.
Ion Cristian EfremInternal Medicine and Gastroenterology, University of Medicine and Pharmacy of Craiova, Craiova, ROU.
Adina MitreaDiabetes and Endocrinology, University of Medicine and Pharmacy of Craiova, Craiova, ROU.
Diana ClenciuDiabetes and Endocrinology, University of Medicine and Pharmacy of Craiova, Craiova, ROU.
Stefan D LazarInfectious Diseases, Clinic Hospital of Tropical and Infection Diseases "Dr. Victor Babes", Bucharest, ROU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectives

methodsWe collected retrospectively available data for all patients hospitalised between January 1, 2021, and December 31, 2023. The characteristics of the patients who died after the CDI (

resultsIn the three-year interval mentioned above, 1086 patients had the main or secondary diagnosis of CDI. Of these, 97 patients (8.93%) died. The overall mortality for the same period was 2.62%. Eight patients (8.24%) who died had the primary diagnosis of CDI, while in the entire group, the percentage of patients with a primary diagnosis was 54.7%. Statistically significant differences between the groups of deceased and survivor patients were found for the following parameters: age (p<0.001, 95% CI (confidence interval): 12.5-20.5), previous CDI episodes (p=0.033, 95% CI: 0.014-0.329), and for the following parameters measured at admission: systolic blood pressure, quick sepsis-related organ failure assessment (qSOFA), leucocyte count, haemoglobin, creatinine, albumin, potassium, INR (international normalised ratio), CRP (C-reactive protein), fibrinogen, and procalcitonin. The number of hospitalisation days for the patients who died was significantly higher (p<0.001, 95% CI: 4.3-12.6.).

conclusionsWe identified the characteristics that significantly differentiated the patients who died from those who survived. Mortality is significantly higher in the group of patients with CDI than that in the other hospitalised patients.

Indexed as

clostridioides difficiledeathdiarrheamortalityunfavourable prognostic

Identifiers

PMID39717327
PMCPMC11666302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.