Evidence map›Paper›PMID 39716808›Full record

ArticleJournal of the science of food and agriculture2025

Ultrasound-assisted extraction versus traditional Soxhlet apparatus for the obtention of polyphenols, carotenoids and tocopherols from Tagetes erecta L. flowers.

Sonia Núñez, Marta Sofía Valero, Ahmed M Mustafa, Giovanni Caprioli, Filippo Maggi, Carlota Gómez-Rincón, Víctor López

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of the science of food and agriculture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Vasorelaxant effects of the edible flowersPharmaceutical biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sonia NúñezDepartment of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Zaragoza, Spain.ORCID https://orcid.org/0000-0003-4986-5286
Marta Sofía ValeroInstituto Agroalimentario de Aragón, IA2, Universidad de Zaragoza-CITA, Zaragoza, Spain.ORCID https://orcid.org/0000-0002-2231-7565
Ahmed M MustafaChemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Camerino, Italy.ORCID https://orcid.org/0000-0002-1533-1553
Giovanni CaprioliChemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Camerino, Italy.
Filippo MaggiChemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Camerino, Italy.ORCID https://orcid.org/0000-0003-1375-4744
Carlota Gómez-RincónDepartment of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Zaragoza, Spain.ORCID https://orcid.org/0000-0003-3982-2282
Víctor LópezDepartment of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Zaragoza, Spain.

Funding

Phyto-Pharm group (ref. B44_20R) Goverment of AragonUniversidad San Jorge Proyecto Interno 2223025
6 · The paper itself

Abstract

backgroundTagetes erecta L., commonly known as American marigold, serves as a food plant used for the extraction of carotenoids such as lutein, employed both as culinary ingredient in certain dishes and for its ornamental and medicinal applications. Two extraction techniques, Soxhlet and ultrasound-assisted extraction (UAE), were used on two cultivars (yellow and orange) of T. erecta. Polyphenols were quantified using HPLC-tandem mass spectrometry, whereas carotenoids and tocopherols were determined using HPLC-diode array detection. Biological activity for antioxidant and antiglycation properties was carried out.

resultsThe best extraction yield was obtained for UAE (7.51% and 6.83% for yellow and orange flowers), corresponding with the largest amounts of polyphenols quantified. The highest content of tocopherols was obtained in the yellow cultivar extracted by Soxhlet (6499.3 ± 21.2 and 4671.0 ± 92.9 mg kg

conclusionBoth extraction techniques showed interesting results in terms of bioactivity and compounds obtention. © 2024 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

CarotenoidsChemical FractionationFlowersPlant ExtractsPolyphenolsTagetesTocopherolsAntioxidantsChromatography, High Pressure LiquidAntioxidantsCarotenoidsPlant ExtractsPolyphenolsTocopherolsedible flowersgreen extractionnatural pigmentSoxhlet extractionultrasound‐assisted extraction

Identifiers

PMID39716808
PMCPMC11949861

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.