Evidence map›Paper›PMID 39716721›Full record

ReviewAsian journal of andrology2025

Medical treatment prior to micro-TESE.

Sujoy Dasgupta, Thanh Sang Le, Amarnath Rambhatla, Rupin Shah, Ashok Agarwal

Abstract readReview
In one paragraph

Review in Asian journal of andrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sujoy DasguptaDepartment of Reproductive Medicine, Genome Fertility Centre, Kolkata 700025, West Bengal, India.
Thanh Sang LeGlobal Andrology Forum, Moreland Hills, OH 44022, USA.
Amarnath RambhatlaGlobal Andrology Forum, Moreland Hills, OH 44022, USA.
Rupin ShahGlobal Andrology Forum, Moreland Hills, OH 44022, USA.
Ashok AgarwalGlobal Andrology Forum, Moreland Hills, OH 44022, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractExcept in cases of hypogonadotropic hypogonadism, the use of medical therapy before microsurgical testicular sperm extraction (micro-TESE) is controversial. In some studies, hormone therapy has been shown to improve the possibility of sperm retrieval during micro-TESE and even lead to the presence of sperm in the ejaculate in some cases, thereby obviating the need for micro-TESE. However, their routine use before micro-TESE in cases of nonobstructive azoospermia (NOA) being associated with hypergonadotropic hypogonadism and eugonadism (normogonadotropic condition) has not been supported with robust evidence. In this review, we discuss different types of medical therapy used before micro-TESE for NOA, their risks and benefits, and the available evidence surrounding their use in this setting.

Indexed as

AzoospermiaSperm RetrievalHumansHypogonadismMaleMicrosurgeryaromatase inhibitorsgonadotropinsmale infertilitymicrosurgical testicular sperm extractionnonobstructive azoospermiaselective estrogen receptor modulatorssuccessful sperm retrieval

Identifiers

PMID39716721
PMCPMC12112922

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.