ArticleBiomedical engineering online2024
Experimental and computational evaluation of knee implant wear and creep under in vivo and ISO boundary conditions.
Article in Biomedical engineering online, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Evidence-informed methodological approaches for coupled neuromusculoskeletal-finite element analysis workflows in orthopaedic biomechanics.Frontiers in bioengineering and biotechnology · 2026Article
- Biosensor-Integrated Tibial Components in Total Knee Arthroplasty: A Narrative Review of Innovations, Challenges, and Translational Frontiers.Bioengineering (Basel, Switzerland) · 2025Review
- Transfer of patients' tibiofemoral kinematics and loads to a six-degree-of-freedom (6-DOF) joint simulator under consideration of virtual ligaments.Scientific reports · 2025Article
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Authors and funding
7 authors.
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Abstract
backgroundExperimental knee implant wear testing according to ISO 14243 is a standard procedure, but it inherently possesses limitations for preclinical evaluations due to extended testing periods and costly infrastructure. In an effort to overcome these limitations, we hereby develop and experimentally validate a finite-element (FE)-based algorithm, including a novel cross-shear and contact pressure dependent wear and creep model, and apply it towards understanding the sensitivity of wear outcomes to the applied boundary conditions.
methodsSpecifically, we investigated the application of in vivo data for level walking from the publicly available "Stan" data set, which contains single representative tibiofemoral loads and kinematics derived from in vivo measurements of six subjects, and compared wear outcomes against those obtained using the ISO standard boundary conditions. To provide validation of the numerical models, this comparison was reproduced experimentally on a six-station knee wear simulator over 5 million cycles, testing the same implant Stan's data was obtained from.
resultsExperimental implementation of Stan's boundary conditions in displacement control resulted in approximately three times higher wear rates (4.4 vs. 1.6 mm
conclusionsThe FE wear model is suitable for supporting future patient-specific models and development of novel implant designs. Incorporating the Stan data set alongside ISO boundary conditions emphasized the value of using measured kinematics in displacement control for reliably replicating in vivo joint mechanics in wear simulation. Future work should focus on expanding the range of daily activities simulated and addressing model sensitivity to contact mechanics to further enhance predictive accuracy.
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