Evidence map›Paper›PMID 39716105›Full record

SynthesisBMC psychiatry2024

Depression, anxiety and associated factors among cancer patients in Africa; a systematic review and meta-analysis study.

Girum Nakie, Mamaru Melkam, Girmaw Medfu Takelle, Setegn Fentahun, Gidey Rtbey, Fantahun Andualem, Getasew Kibralew, Yilkal Abebaw Wassie, Mulat Awoke Kassa, Techilo Tinsae and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Prescription and use of psychoactive medications among cancer patients and associated factors in lower and upper middle-income countries: systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
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  7. Prevalence of depression and association with quality-of-life among oncology patients at Princess Marina Hospital, Botswana: A cross-sectional study.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Girum NakieDepartment of Psychiatry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia. girumnakie@gmail.com.
Mamaru MelkamDepartment of Psychiatry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Girmaw Medfu TakelleDepartment of Psychiatry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Setegn FentahunDepartment of Psychiatry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Gidey RtbeyDepartment of Psychiatry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Fantahun AndualemDepartment of Psychiatry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Getasew KibralewDepartment of Psychiatry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Yilkal Abebaw WassieDepartment of Medical Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Mulat Awoke KassaDepartments of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia.
Techilo TinsaeDepartment of Psychiatry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Gebresilassie TadesseDepartment of Psychiatry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression and anxiety are the most common types of mental disorders among cancer patients. Many research studies carried out in African countries indicate that anxiety and depression are highly prevalent, but the results vary across regions. Thus, this study aimed to estimate the pooled prevalence and associated factors of depression and anxiety among cancer patients in Africa.

methodsThe databases EMBASE, PubMed, African Journals Online, and Google Scholar were used to identify articles. This systematic review and meta-analysis included 32 (31 for depression and 25 for anxiety) original articles from 11 African countries. To detect publication bias, Egger regression tests and funnel plot analysis were employed. A sensitivity analysis and a subgroup analysis were carried out.

resultsThe pooled prevalence of depression and anxiety among cancer patients was found to be 53.21% (95% CI: 47.47-58.94) and 53.32% (95% CI: 46.85, 59.80) respectively. Across regions, the prevalence of depression among cancer patients was 60.03 (95% CI: 55.85-64.21), 53.59 (95% CI: 45.31-61.87), and 43.92 (95% CI: 36.17-51.67) in North, East, and West Africa, respectively. The pooled prevalence of anxiety among cancer patients was 64.85 (95% CI: 54.81-74.88) in North Africa, 49.53 (95% CI: 40.72-58.33) in East Africa, and 46.23 (95% CI: 38.98-53.48) in West Africa. Advanced stages of cancer (AOR = 3.8; 95% CI: 1.73, 8.42), less educated (AOR = 2.57; 95% CI: 1.28-5.14), and having no financial support (AOR = 2.03; 95% CI: 1.12, 3.67) were factors associated with depression. Advanced stages of cancer (AOR = 5.44; 95% CI: 1.95, 15.18) and no financial assistance (AOR = 2.88; 95% CI: 1.79, 4.63) were factors associated with anxiety.

conclusionDepression and anxiety among cancer patients are highly prevalent in Africa. Being at an advanced stage of cancer, low educational attainment, and not having financial support were all associated with depression symptoms; in addition, having advanced cancer and not having financial support were also associated with anxiety symptoms. Therefore, it is critical to screen cancer patients for anxiety and depression and provide them with appropriate interventions when these conditions arise.

Indexed as

AnxietyDepressionNeoplasmsAfricaAnxiety DisordersDepressive DisorderHumansPrevalenceAfricaAnxietyA systematic reviewCancerDepressionMeta-analysis

Identifiers

PMID39716105
PMCPMC11668085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.