Evidence map›Paper›PMID 39716012›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Proteomics-Based Analysis of Laser-Capture Micro-dissected, Formalin-Fixed Paraffin-Embedded Tissue Samples.

Teresa Mendes Maia, Delphi Van Haver, Sara Dufour, Malaïka Van der Linden, Amélie Dendooven, Francis Impens, Simon Devos

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Teresa Mendes MaiaVIB-UGent Center for Medical Biotechnology, Ghent, Belgium.
Delphi Van HaverVIB-UGent Center for Medical Biotechnology, Ghent, Belgium.
Sara DufourVIB-UGent Center for Medical Biotechnology, Ghent, Belgium.
Malaïka Van der LindenDepartment of Pathology, Ghent University Hospital, Ghent, Belgium.
Amélie DendoovenDepartment of Pathology, Ghent University Hospital, Ghent, Belgium.
Francis ImpensVIB-UGent Center for Medical Biotechnology, Ghent, Belgium.
Simon DevosVIB-UGent Center for Medical Biotechnology, Ghent, Belgium. simon.devos@vib-ugent.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to bring spatial resolution to omics studies enables a deeper understanding of cell populations and interactions in biological tissues. In the case of proteomics, single-cell and spatial approaches have been particularly challenging, due to limitations in sensitivity and throughput relative to other omics fields. Recent developments at the level of sample handling, chromatography, and mass spectrometry have set the stage for proteomics to be established in these new disciplines.

Indexed as

FormaldehydeLaser Capture MicrodissectionParaffin EmbeddingProteomicsTissue FixationAnimalsChromatography, LiquidHumansMass SpectrometryProteomeFormaldehydeProteomeAmyloidosisDIAFFPELCMSpatial proteomics

Identifiers

PMID39716012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.