ArticlePediatric surgery international2024
Surgical management of children with Burkitt's lymphoma involving the gastrointestinal tract.
Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Updates in Evidence-Based Decision Making for Upfront Surgical Interventions in Paediatric Lymphoma.European journal of haematology · 2026Review
- Primary Gastrointestinal B-Cell Lymphomas: A Clinicopathological Review.Journal of hematology · 2025Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the clinical characteristics and surgical management of children with Burkitt's lymphoma (BL) involving the gastrointestinal tract.
methodsA retrospective analysis was conducted on 87 pediatric patients diagnosed with BL involving the gastrointestinal tract and treated surgically at Beijing Children's Hospital (2008-2022). All patients were histopathologically confirmed with BL and diagnosed with gastrointestinal involvement through imaging studies and surgery. Clinical data were reviewed and analyzed.
resultsAmong 87 patients, 79 were male and 8 were female, with an average age of 6.8 ± 3.3 years. Predominant clinical manifestations included abdominal pain (74/87, 85.1%) and abdominal mass (45/87, 51.7%). The ileocecal region (31/87, 35.6%) was the most frequent involvement site. The presence of intussusception (58/87, 66.7%) was the main indication for surgery, of which 56 (56/58, 96.6%) underwent enterectomy and anastomosis. Twenty-two (22/87, 25.3%) patients underwent surgery for abdominal mass, with 15 (15/22, 68.2%) receiving an open biopsy. During the follow-up period, 2 patients (2/83, 2.4%) experienced recurrence, 4 patients (4/83, 4.8%) required reoperation, and no deaths were reported.
conclusionThe main surgical indications for gastrointestinal BL are intussusception and abdominal mass. Surgery plays a crucial role in resolving intussusception, clarifying the diagnosis, and ultimately facilitating the timely initiation of chemotherapy without delay.
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