Evidence map›Paper›PMID 39715877›Full record

ArticleNature human behaviour2025

Polygenic prediction of occupational status GWAS elucidates genetic and environmental interplay in intergenerational transmission, careers and health in UK Biobank.

Evelina T Akimova, Tobias Wolfram, Xuejie Ding, Felix C Tropf, Melinda C Mills

Abstract read
In one paragraph

Article in Nature human behaviour, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Evelina T Akimova *Department of Sociology, Purdue University, West Lafayette, IN, USA. eakimova@purdue.edu.ORCID 0000-0001-8733-3745
Tobias Wolfram *Department of Sociology, University of Bielefeld, Bielefeld, Germany. twolfram.eisenach@gmail.com.ORCID 0000-0002-0280-2512
Xuejie DingLeverhulme Centre for Demographic Science, Nuffield Department of Population Health and Nuffield College, University of Oxford, Oxford, UK.
Felix C TropfDepartment of Sociology, Purdue University, West Lafayette, IN, USA.ORCID 0000-0003-2445-515X
Melinda C MillsLeverhulme Centre for Demographic Science, Nuffield Department of Population Health and Nuffield College, University of Oxford, Oxford, UK.

Funding

Leverhulme Trust RC-2018-003
6 · The paper itself

Abstract

Socioeconomic status (SES) impacts health and life-course outcomes. This genome-wide association study (GWAS) of sociologically informed occupational status measures (ISEI, SIOPS, CAMSIS) using the UK Biobank (N = 273,157) identified 106 independent single-nucleotide polymorphisms of which 8 are novel to the study of SES. Genetic correlations with educational attainment (r

Indexed as

EmploymentGene-Environment InteractionHealth StatusMultifactorial InheritanceOccupationsSocial ClassAdultAgedBiological Specimen BanksEducational StatusFemaleGenome-Wide Association StudyHumansMaleMiddle AgedPolymorphism, Single Nucleotide

Identifiers

PMID39715877
PMCPMC11860221

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.