ArticleScientific data2024
Transcriptional signatures of secondary hair follicles during annual cashmere growth.
Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Molecular characterization and functional insights of secondary hair follicles across the cashmere growth cycle.BMC genomics · 2026Article
- Epigenetic and transcriptional profiling of secondary hair follicle stem cells during cashmere growth.Scientific data · 2026Article
- Molecular Regulation of Secondary Hair Follicle Stem Cell by S100a4 in Cashmere Goat.International journal of molecular sciences · 2026Article
- Molecular mechanisms underlying cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats.Frontiers in veterinary science · 2025Article
- Transcriptional signatures of secondary hair follicles during annual cashmere growth.Scientific data · 2024Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cashmere grows from the secondary hair follicles (SHFs) that synchronously regenerate and degenerate in a circannual rhythm. Most studies examining factors related to cashmere growth have been performed on goat skin. However, the molecular properties and regulators preferentially expressed in SHFs are less clear. In this study, we isolated the SHFs from skin under a dissecting microscope and analysed the molecular signatures across the annual growth. It demonstrated the transcriptional profile of the isolated SHFs could accurately decipher the growth state and unequivocally distinguish three phases of the cashmere growth. We identified 1,289 molecular signatures that were differentially expressed between different phases. Real-time PCR verified the accuracy and reliability of our sequencing data for the representative genes. Taken together, the transcriptional profiles and identified molecular signatures extended previous findings, and provided a variety of promising targets for cashmere production, thereby offering valuable starting points for future work.
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