Evidence map›Paper›PMID 39715430›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

RNAi of the elastomeric protein resilin reduces jump velocity and resilience to damage in locusts.

Stephen M Rogers, Darron A Cullen, David Labonte, Gregory P Sutton, Jozef J M Vanden Broeck, Malcolm Burrows

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stephen M Rogers *Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom.ORCID 0000-0002-6973-3996
Darron A Cullen *Department of Biology, Zoological Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0000-0002-6287-5086
David LabonteDepartment of Bioengineering, Imperial College London, London SW7 2PD, United Kingdom.ORCID 0000-0002-1952-8732
Gregory P SuttonSchool of Natural Sciences, University of Lincoln, Lincoln LN6 7TS, United Kingdom.ORCID 0000-0002-3099-9842
Jozef J M Vanden BroeckDepartment of Biology, Zoological Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0000-0001-7653-0516
Malcolm BurrowsDepartment of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom.ORCID 0000-0003-1386-5065

Funding

cambridgeuniversity | Clare College, University of Cambridge Denman Baynes SRFDOD | USA | AFC | CCDC | ARO | Life Sciences Division, Army Research Office (Life Sciences Division ARO) W911NF-15-038Fonds Wetenschappelijk Onderzoek (FWO) G090919NFonds Wetenschappelijk Onderzoek (FWO) G0F2417NRoyal Society (The Royal Society) UF130507UKRI | Medical Research Council (MRC) MR/T046619/1
6 · The paper itself

Abstract

Resilin, an elastomeric protein with remarkable physical properties that outperforms synthetic rubbers, is a near-ubiquitous feature of the power amplification mechanisms used by jumping insects. Catapult-like mechanisms, which incorporate elastic energy stores formed from a composite of stiff cuticle and resilin, are frequently used by insects to translate slow muscle contractions into rapid-release recoil movements. The precise role of resilin in these jumping mechanisms remains unclear, however. We used RNAi to reduce resilin deposition in the principal energy-storing springs of the desert locust (

Indexed as

GrasshoppersInsect ProteinsRNA InterferenceAnimalsBiomechanical PhenomenaGene Knockdown TechniquesInsect Proteinsresilinbiomechanicselastic energy storageinsect locomotionmuscle-spring interaction

Identifiers

PMID39715430
PMCPMC11725850

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.