ArticleJournal of veterinary internal medicine
Clinical characterization of a novel episodic ataxia in young working Cocker Spaniels.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Clinical characterization of a novel episodic ataxia in young working Cocker Spaniels.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpisodic ataxias (EAs) are a rare group of paroxysmal movement disorders (PMD) described in human medicine with only one suspected case described in veterinary literature. HYPOTHESIS/
objectivesThis study aimed to provide clinical description of a suspected primary EA in working Cocker Spaniel (WCS) dogs. ANIMALS: Seven WCS dogs with suspected primary EA.
methodsDescriptive, retrospecitve, multicenter study. Clinical signs, video footage, investigations, treatment, and outcome were reviewed. Owners of affected dogs were invited to complete a questionnaire.
resultsThe mean age at clinical onset was 4 months. Signs were acute and included episodic body swaying, titubation, cerebellar ataxia, wide-base stance, and hypermetria, all while mentation remained unaltered. Neither autonomic nor vestibular signs nor hyperkinetic movements were observed. Duration of episodes ranged from 30 minutes up to 24 hours, and their frequency varied from weekly to once every 5 months. When investigations were performed, results revealed no abnormalities except for 1 dog that had increased gluten antibody titers. None of the dogs deteriorated, and in dogs with available follow-up (5/7) the frequency of episodes decreased or completely resolved, from which the majority (4/5) received gluten-free diet. CONCLUSION AND CLINICAL IMPORTANCE: A novel PMD was identified in young WCS, manifesting as EA. The condition is suspected to have a primary (genetic) etiology, although the cause of this manifestation has not yet been identified. Episodic ataxia in our WCS had a good prognosis. Veterinarians must be aware of this presentation, and further investigations are needed to determine the origin of the clinical signs.
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