Evidence map›Paper›PMID 39714188›Full record

ArticlemBio2025

Ethanolamine-induced assembly of microcompartments is required for

Dana S Franklin, Yi-Wei Chen, Yimin Chen, Manuel Wittchen, Angela Agnew, Alexis Luu, Julian P Whitelegge, Z Hong Zhou, Andreas Tauch, Asis Das and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Isolation and Visualization Fusobacterium nucleatum Microcompartments.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. MedComm · 2025
    Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Dana S FranklinMolecular Biology Institute, University of California, Los Angeles, California, USA.
Yi-Wei ChenDivision of Oral & Systemic Health Sciences, School of Dentistry, University of California, Los Angeles, California, USA.
Yimin ChenDivision of Oral & Systemic Health Sciences, School of Dentistry, University of California, Los Angeles, California, USA.
Manuel WittchenCenter for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany.
Angela AgnewDepartment of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA.
Alexis LuuDivision of Oral & Systemic Health Sciences, School of Dentistry, University of California, Los Angeles, California, USA.
Julian P WhiteleggePasarow Mass Spectrometry Laboratory, NPI-Semel Institute, University of California Los Angeles, Los Angeles, California, USA.
Z Hong ZhouDepartment of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-8373-4717
Andreas TauchCenter for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany.
Asis DasDepartment of Medicine, Neag Comprehensive Cancer Center, School of Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA.
Hung Ton-ThatMolecular Biology Institute, University of California, Los Angeles, California, USA.ORCID 0000-0003-1611-0469

Funding

MULTIDISCIPLINARY TRAINING IN MICROBIAL PATHOGENESIST32AI007323 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Peter John Bradley · 1988 to 2026
$8.6M
UCLA Dentist-Scientist and Oral Health-Researcher Training ProgramT90DE030860 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TON-THAT, HUNG, WONG, DAVID T · 2021 to 2025
$2.1M
Virulence determinants of Fusobacterium nucleatumR01DE026758 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TON-THAT, HUNG · 2017 to 2021
$2.0M
Metabolic modulation of Fusobacterium nucleatum virulenceR21DE032906 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TON-THAT, HUNG · 2023 to 2024
$605k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) T32AI007323HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) DE032906, DE026758HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) T90DE030860NIAID NIH HHS T32 AI007323NIDCR NIH HHS R01 DE026758NIDCR NIH HHS R21 DE032906NIDCR NIH HHS T90 DE030860
6 · The paper itself

Abstract

Many bacteria metabolize ethanolamine as a nutrient source through cytoplasmic organelles named bacterial microcompartments (BMCs). Here we investigated the molecular assembly, regulation, and function of BMCs in IMPORTANCE: The oral anaerobe

Indexed as

EthanolamineFusobacterium nucleatumAnimalsBacterial ProteinsFemaleFusobacterium InfectionsGene DeletionGene Expression Regulation, BacterialMicePregnancyVirulenceBacterial ProteinsEthanolaminebacterial microcompartmentelectron microscopyethanolamine utilizationFusobacterium nucleatumpreterm birth

Identifiers

PMID39714188
PMCPMC11796344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.