ArticleNano letters2025
Protein-Enabled Size-Selective Defect-Sealing of Atomically Thin 2D Membranes for Dialysis and Nanoscale Separations.
Article in Nano letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Sieving Hydrogen Isotopes via Machine Learning Assisted Chemical Vapor Deposition (CVD) of High-Quality Monolayer Hexagonal Boron Nitride (h-BN) on Iron Foils.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Proton Selective Nanoporous Atomically Thin Graphene Membranes for Vanadium Redox Flow Batteries.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Article
- Size-Selective Nanoporous Atomically Thin Graphene Separators for Lithium-Sulfur Batteries.ACS applied materials & interfaces · 2025Article
- Scalable Bottom-Up Synthesis of Nanoporous Hexagonal Boron Nitride (Nano letters · 2025Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atomically thin 2D materials present the potential for advancing membrane separations via a combination of high selectivity (from molecular sieving) and high permeance (due to atomic thinness). However, the creation of a high density of precise nanopores (narrow-size-distribution) over large areas in 2D materials remains challenging, and nonselective leakage from nanopore heterogeneity adversely impacts performance. Here, we demonstrate protein-enabled size-selective defect sealing (PDS) for atomically thin graphene membranes over centimeter scale areas by leveraging the size and reactivity of permeating proteins to preferentially seal larger nanopores (≥4 nm) while preserving a significant amount of smaller nanopores (via steric hindrance). Our defect-sealed nanoporous atomically thin membranes (NATMs) show stability up to ∼35 days during size-selective diffusive separations with a model dialysis biomolecule fluorescein isothiocyanate (FITC)-Ficoll 70 in phosphate buffer saline (PBS) solution as well as outperform state-of-the-art commercially available dialysis membranes (molecular-weight-cutoff ∼3.5-5 kDa and ∼8-10 kDa) with significantly higher permeance for smaller solutes KCl (∼0.66 nm) ∼5.1-6 × 10
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