ArticleThe application of clinical genetics2024
Bilateral Wilms Tumor - Case Report of a Patient with Family History.
Article in The application of clinical genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wilms' tumor (WT) is the most common renal neoplasm in children. Despite its rapid growth, it is often asymptomatic. It most commonly occurs between the ages of 3 and 5, more frequently in girls. Numerous studies report an association between the occurrence of Wilms' tumor and genetic background. Treatment of bilateral Wilms' tumor (BWT) presents several challenges. Recent studies raise the issue of the influence of genetics on the development of BWT. We believe that our case report is innovative as it provides information on a rare clinical presentation and comprehensively addresses the potential impact of genetic studies on favorable treatment outcomes, which are discussed only in limited detail in the literature. The case description concerns a 2-year-old and a 5-month-old patient who presented with his mother due to a change in abdominal contour. In the medical history, the boy's mother had been treated for WT. Imaging of the abdominal cavity revealed the presence of pathological tissue changes in both kidneys. Based on this, stage V Wilms' tumor was diagnosed. The boy underwent a right-sided tumor nephrectomy followed by a left-sided heminephrectomy. He also received pre- and post-operative chemotherapy. Genetic testing revealed a deletion fragment of exon 8 and exons 9-10 on one allele of the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.