Evidence map›Paper›PMID 39713311›Full record

ArticlebioRxiv : the preprint server for biology2024

tet2 and tet3 regulate cell fate specification and differentiation events during retinal development.

Shea A Heilman, Hannah C Schriever, Dennis Kostka, Kristen M Koenig, Jeffrey M Gross

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Shea A HeilmanDepartment of Ophthalmology, The Louis J. Fox Center for Vision Restoration, The McGowan Institute for Regenerative Medicine, The University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.
Hannah C SchrieverDepartment of Computational Biology, The University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.
Dennis KostkaDepartment of Computational Biology, The University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.
Kristen M KoenigDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX, United States of America.
Jeffrey M GrossDepartment of Ophthalmology, The Louis J. Fox Center for Vision Restoration, The McGowan Institute for Regenerative Medicine, The University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Yuanyuan Chen · 1989 to 2026
$17.8M
Interdisciplinary Visual Sciences (IVS) Traininig ProgramT32EY017271 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Marlene Behrmann, Paul R. Kinchington · 2008 to 2026
$3.6M
DNA Methylation and Hydroxymethylation During Retinal Development and Stem Cell MaintenanceR01EY029031 · NEI · UNIVERSITY OF TEXAS AT AUSTIN · PI GROSS, JEFFREY · 2018 to 2022
$1.9M
NEI NIH HHS P30 EY008098NEI NIH HHS R01 EY029031NEI NIH HHS T32 EY017271
6 · The paper itself

Abstract

Tet enzymes are epigenetic modifiers that impact gene expression via 5mC to 5hmC oxidation. Previous work demonstrated the requirement for Tet and 5hmC during zebrafish retinogenesis.

Identifiers

PMID39713311
PMCPMC11661121

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.