Evidence map›Paper›PMID 39713295›Full record

ArticlebioRxiv : the preprint server for biology2024

Bicoid-nucleosome competition sets a concentration threshold for transcription constrained by genome replication.

Eleanor A Degen, Corinne Croslyn, Niall M Mangan, Shelby A Blythe

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Eleanor A DegenInterdisciplinary Biological Sciences Graduate Program, Northwestern University, Evanston Illinois 60208, USA.ORCID 0000-0002-0832-4507
Corinne CroslynInterdisciplinary Biological Sciences Graduate Program, Northwestern University, Evanston Illinois 60208, USA.ORCID 0000-0002-9190-7390
Niall M ManganDepartment of Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, Illinois 60208, USA.ORCID 0000-0002-3491-8341
Shelby A BlytheDepartment of Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, USA.ORCID 0000-0003-4986-2579

Funding

CELLULAR &MOLECULAR BASIS OF DISEASE TRAINING PROGRAMT32GM008061 · NIGMS · NORTHWESTERN UNIVERSITY · PI CARTHEW, RICHARD W. · 1985 to 2022
$17.1M
Defining epigenetic mechanisms for embryonic patterningR01HD101563 · NICHD · NORTHWESTERN UNIVERSITY · PI Shelby Alexander Blythe · 2021 to 2026
$2.0M
NICHD NIH HHS R01 HD101563NIGMS NIH HHS T32 GM008061
6 · The paper itself

Abstract

Transcription factors (TFs) regulate gene expression despite constraints from chromatin structure and the cell cycle. Here we examine the concentration-dependent regulation of

Identifiers

PMID39713295
PMCPMC11661180

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.