ArticleGlobal heart2024
Association Between the Albumin-Bilirubin (ALBI) Score and All-cause Mortality Risk in Intensive Care Unit Patients with Heart Failure.
Article in Global heart, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Association between albumin-bilirubin score and all-cause mortality in patients with acute respiratory failure: a cohort study based on the MIMIC-IV database.Journal of thoracic disease · 2026Article
- Association between albumin-bilirubin (ALBI) score and all-cause mortality in critically ill patients with pulmonary embolism: a cohort study based on the MIMIC-IV database.Journal of thoracic disease · 2026Article
- Association of albumin-bilirubin score with clinical severity and outcome in patients with decompensated heart failure: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- Prognostic Value of Albumin-Bilirubin Score in Acute Pancreatitis: Insights From the MIMIC-IV Database.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- The association of the ALBI score with disease severity and perinatal outcomes in the preeclampsia spectrum.BMC pregnancy and childbirth · 2026Article
- Association of the Albumin-Bilirubin score with 7-day incident delirium risk following bloodstream infection in critically ill adults: evidence from a propensity-weighted cohort.BMC infectious diseases · 2026Article
- Correlation between albumin-bilirubin score and comorbidity of cardiovascular disease and chronic kidney disease: insights from NHANES 2011-2018.European journal of medical research · 2026Article
- Nutritional-inflammatory-metabolic indices associated with in-hospital mortality in acute kidney injury patients undergoing continuous renal replacement therapy: dose-response analysis and machine learning-based risk stratification.Frontiers in nutrition · 2026Article
- Article
- Association between ALBI score and stroke risk and all-cause mortality: 2011 to 2018 NHANES.Medicine · 2025Article
- Article
- Assessing Venous Congestion in Acute and Chronic Heart Failure: A Review of Splanchnic, Cardiac and Pulmonary Ultrasound: Part 1: Conventional B-Mode, Colordoppler, and Vexus Protocol.Journal of clinical medicine · 2025Review
- Redefining the albumin-bilirubin score: Predictive modeling and multidimensional integration in liver and systemic disease.World journal of gastroenterology · 2025Article
- Predictive role of the Albumin-Bilirubin score in ICU patients with cirrhosis and sepsis: insights from a large retrospective cohort.BMC gastroenterology · 2025Article
- Development, Validation, and Deployment of a Time-Dependent Machine Learning Model for Predicting One-Year Mortality Risk in Critically Ill Patients with Heart Failure.Bioengineering (Basel, Switzerland) · 2025Article
- Association of albumin-bilirubin grade with short- and long-term mortality in patients with heart failure: a cohort study using restricted cubic splines and propensity score matching.BMC cardiovascular disorders · 2025Article
- Association between the platelet-albumin-bilirubin score and all-cause mortality in ICU-admitted heart failure patients: a retrospective cohort analysis and machine learning-based prognostic modeling.Frontiers in cardiovascular medicine · 2025Article
- Independent prognostic importance of endothelial activation and stress index (EASIX) in critically ill patients with heart failure: modulating role of inflammation.Frontiers in medicine · 2025Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The albumin-bilirubin (ALBI) score has demonstrated prognostic value in a range for liver and heart diseases. However, its association with all-cause mortality in intensive care unit (ICU) patients with heart failure remains uncertain. Objective: This study sought to investigate the relationship between the ALBI score and the risk of all-cause mortality in ICU patients with heart failure. Methods and results: The ICU patients diagnosed with heart failure were selected from the Medical Information Mart for Intensive Care IV database (MIMIC-IV, version 2.2) and stratified into tertiles according to their ALBI scores. The primary outcome of interest was the occurrence of all-cause mortality within 365 days post-discharge. The analysis encompassed a cohort of 4,239 patients, with Kaplan-Meier curves indicating that individuals with higher ALBI levels exhibited an elevated risk of all-cause mortality (log-rank p < 0.001). Multivariate adjusted Cox regression and subgroup analysis demonstrated that individuals in T2 (hazard ratio (HR) 1.09, 95% CI 0.99-1.21) and T3 (HR 1.17, 95% CI 1.02-1.34) had an increased risk of mortality compared to individuals in T1 (p for trend < 0.001), and each incremental tertile in ALBI was linked to a 10% rise in mortality risk, while each individual unit increase in ALBI was associated with a 36% increase in mortality risk. This relationship was consistently observed across most subgroups, except for using or not using inotropes or vasopressors, different ages, different creatinine levels. The restricted cubic spline (RCS) analysis indicated a linear relationship between ALBI levels and the risk of all-cause mortality. Conclusion: The ALBI scores are independently associated with the risk of all-cause mortality in ICU patients with heart failure, particularly in those not using inotropes or vasopressors, younger patients, and with lower levels of creatinine. ALBI may help identify high-risk patients and optimize risk stratification in this population.
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