Evidence map›Paper›PMID 39713155›Full record

ArticlePeerJ2024

Correlation and mediation analysis between plasmapheresis donation behavior and bone mineral density and bone metabolism biomarkers: a cross-sectional study based on plasmapheresis donors at high risk of osteoporosis in China.

Wan Li, Jia Liu, Changqing Li, Hui Yang, Yating Yang, Zhiwei Li, Shouqiang Yang, Yuan He, Guanglin Xiao, Ya Wang and 1 more

Abstract read
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wan Li *Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu, China.
Jia Liu *West China Second University Hospital, SCU, Chengdu, China.
Changqing LiInstitute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu, China.
Hui YangNanyue Biopharmaceutical Corporation Ltd. China, Hengyang, China.
Yating YangGrand Shuyang Life Sciences(Chengdu)Co., Ltd., Chengdu, China.
Zhiwei LiLinwu Plasmapheresis Station, Nanyue Biopharming Co., Ltd., Linwu, China.
Shouqiang YangJiange Plasmapheresis Station, Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd., Jiange, China.
Yuan HeJiange Plasmapheresis Station, Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd., Jiange, China.
Guanglin XiaoInstitute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu, China.
Ya WangInstitute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu, China.
Yongjun ChenInstitute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As a group of more than 3.67 million people, the bone health of Chinese plasmapheresis donors, which the main population is also a risk group of osteoporosis (OP), has raised concerns. Therefore, this article investigates the relationship between bone mineral density (BMD), bone metabolism indicators, and plasmapheresis donation behavior among some high-risk plasmapheresis donors for OP in China, and further explores the mediating factors through reasonable statistical methods. Methods: Recruiting long-term and highly active plasmapheresis donors and new donors to measure the total calcium, albumin (ALB), 25-hydroxy vitamin D (25OHD), parathyroid hormone (PTH), type I procollagen amino-terminal peptide (P1NP), and type I collagen carboxy-terminal peptide ( Results: Compared to new donors, repeat donors have a lower 25OHD, Conclusion: Long-term and frequently plasmapheresis donation does not affect the bone mass of even elderly donors at high risk for osteoporosis under the existing collection standards and anticoagulant use in China. However, as a self-regulation way, it does increase the osteogenic activity of the body.

Indexed as

BiomarkersBone DensityOsteoporosisPlasmapheresisAdultBlood DonorsCalciumChinaCollagen Type ICross-Sectional StudiesFemaleFerritinsHumansMaleMiddle AgedParathyroid Hormone25-hydroxyvitamin DBiomarkersCalciumCollagen Type Icollagen type I trimeric cross-linked peptideFerritinsParathyroid HormonePeptide FragmentsPeptidesProcollagenprocollagen Type I N-terminal peptideVitamin DBMDFerritinOsteoporosisPlasmapheresis donationVitamin D

Identifiers

PMID39713155
PMCPMC11663400

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.