ArticleACS measurement science au2024
Electrochemical Profiling of vWFA2 for Systemic Inflammatory State Detection.
Article in ACS measurement science au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Pathophysiology-guided biomarkers and therapeutics for precision trauma medicine in polytrauma with musculoskeletal injuries.Military Medical Research · 2026Review
- Dual-cytokine profiling of inflammatory states using a rapid electroanalytical device as a point-of-care sensor platform.Mikrochimica acta · 2026Article
- A Non-Faradaic Impedimetric Label-Free Immunosensor Integrated with PCCODE Logic for Stratified Monitoring of Post-COVID Conditions.ACS measurement science au · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This research aims to develop a portable biosensor device for quickly detecting vWFA2, a biomarker for inflammatory conditions. This sensor could dramatically change detection methods and lead us to improve the sensitivity of our tests to overcome the limitations of conventional detection methods. Our label-free biomolecular assay is constructed on an Au-ZnO electrode surface and uses electrochemical impedance spectroscopy (EIS) to measure the capacitive change in impedance, revealing the binding effects of the target vWFA2, to the capture probe. Our developed biosensor platform exhibits greater sensitivity and specificity, covering a wide dynamic range of 750-24,000 pg/mL and showing a strong correlation with inflammatory conditions. This sensor exhibited a greater accuracy ranging from 86-110% for the known spiked concentrations in nondiluted or modified plasma samples. This electrochemical sensor has the potential to advance point-of-care diagnostic methods due to its high sensitivity and rapid response time. The vision behind this research is to develop an electrochemical sensor that can rapidly and accurately detect disease states, thus creating a pivotal prognostic tool in inflammatory state treatment and ultimately mitigating severe mortality and morbidity.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.