Evidence map›Paper›PMID 39712889›Full record

ArticleFrontiers in microbiology2024

β-lactam antibiotics induce metabolic perturbations linked to ROS generation leads to bacterial impairment.

Dongyang Ye, Jing Sun, Ran Jiang, Jiashen Chang, Yiming Liu, Xiangzheng Wu, Luqi Li, Yihan Luo, Juan Wang, Kangkang Guo and 1 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Tylosin Removal Under PbAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Protective role of VitC, Glutathione and Sodium Pyruvate against antibiotic-induced oxidative damage in Escherichia coli.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Beta-lactam antibiotics under light: optical and photochemical characterization.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dongyang Ye *College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Jing Sun *College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Ran JiangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Jiashen ChangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Yiming LiuCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Xiangzheng WuCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Luqi LiLife Science Research Core Services, Northwest A&F University, Yangling, Shaanxi, China.
Yihan LuoCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Juan WangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Kangkang GuoCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Zengqi YangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the impact of antibiotics on bacterial metabolism is crucial for elucidating their mechanisms of action and developing more effective therapeutic strategies. β-lactam antibiotics, distinguished by their distinctive β-lactam ring structure, are widely used as antimicrobial agents. This study investigates the global metabolic alterations induced by three β-lactam antibiotics-meropenem (a carbapenem), ampicillin (a penicillin), and ceftazidime (a cephalosporin)-in

Indexed as

antibioticsE. colimetabolic perturbationsmetabolomicsβ-lactam

Identifiers

PMID39712889
PMCPMC11659197

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.