ArticleCureus2024
Challenges in Diagnosing Hepatic Sarcoidosis: A Case Report.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatic sarcoidosis is rare, and its similarity to liver metastases complicates the diagnosis. This mimicry requires a thorough diagnostic investigations to exclude neoplasia and other granulomatous diseases, particularly tuberculosis. A 36-year-old male presented with a two-month history of right hypochondrial tenderness, anorexia, asthenia, and weight loss. Clinical examination showed hepatomegaly and splenomegaly. A CT scan revealed non-compressive mediastinal lymphadenopathy and nodular hepatosplenomegaly. Liver function tests indicated cholestasis. The differential diagnosis included lymphoma, metastases, tuberculosis, and sarcoidosis. Biological assessments were normal except for elevated serum angiotensin-converting enzyme (120 U/L) and hypoalbuminemia with polyclonal hypergammaglobulinemia. A CT-guided liver biopsy showed non-caseating granulomas. Tuberculosis tests, including acid-fast bacilli, GeneXpert (Cephei Corp., Sunnyvale, CA) cultures, and Quantiferon (QIAGEN, Venlo, Netherlands) were negative. Multidisciplinary discussion supported sarcoidosis based on clinical, biological, radiological, and histological findings. Hepatic sarcoidosis can mimic conditions like tuberculosis and metastases. Accurate diagnosis is crucial for appropriate management, highlighting the need for awareness of atypical presentations.
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Registered trials
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