Evidence map›Paper›PMID 39712694›Full record

ArticleCureus2024

Refractory Tophaceous Gout With Psoriatic Arthritis: A Case Report.

Rui Coelho, Isabel Fonseca Silva, Sara Xavier Pires, Tomás Fonseca

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rui CoelhoInternal Medicine, Unidade Local de Saúde de Santo António, Porto, PRT.
Isabel Fonseca SilvaInternal Medicine, Unidade Local de Saúde de Santo António, Porto, PRT.
Sara Xavier PiresInternal Medicine, Unidade Local de Saúde de Santo António, Porto, PRT.
Tomás FonsecaInternal Medicine, Unidade Local de Saúde de Santo António, Porto, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although gout is a common intermittent crystalline arthropathy, tophaceous gout is a rare condition. Flares of this disease are usually treated with anti-inflammatory drugs followed by control of serum uric acid levels. We present a refractory, severe, tophaceous gout overlapping with psoriatic arthritis, presenting with a hyper-inflamed phenotype resistant to conventional anti-inflammatory and hypouricemic agents. Control of the disease was only achieved after the introduction of IL-1-blocking therapy. This case highlights the need to control inflammation as the first step in gout treatment and underscores the increasing need for personalized therapies in more complex patients.

Indexed as

anakinra treatmentanti-il-1 treatmentpsoriatic arthiritisrefractory gouttophaceous gout

Identifiers

PMID39712694
PMCPMC11661882

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.