Evidence map›Paper›PMID 39712277›Full record

ArticleInternational journal of cardiology. Congenital heart disease2022

Cardiac MRI predictors of right ventricular dysfunction after the Da Silva cone operation for Ebstein's anomaly.

Tarek Alsaied, Carlos Diaz Castrillon, Adam Christopher, Jose Da Silva, Victor O Morell, Lizabeth Lanford, Bryan H Goldstein, Brian Feingold, Thomas Seery, Gaurav Arora and 5 more

Abstract read
In one paragraph

Article in International journal of cardiology. Congenital heart disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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  6. Editor's corner & issue at a glance.International journal of cardiology. Congenital heart disease · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tarek AlsaiedHeart Institute, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Cardiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Carlos Diaz CastrillonDaSilva Center of Ebstein Anomaly, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Adam ChristopherHeart Institute, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Cardiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jose Da SilvaDaSilva Center of Ebstein Anomaly, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Victor O MorellDaSilva Center of Ebstein Anomaly, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Lizabeth LanfordHeart Institute, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Cardiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Bryan H GoldsteinHeart Institute, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Cardiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Brian FeingoldHeart Institute, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Cardiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Thomas SeeryHeart Institute, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Cardiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Gaurav AroraHeart Institute, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Cardiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Arvind HoskoppalHeart Institute, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Cardiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jennifer A JohnsonHeart Institute, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Cardiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Sameh TadrosDepartment of Radiology, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Laura J OlivieriDivision of Cardiology, Children's National Hospital, Washington, DC, USA.
Luciana De Fonseca Da SilvaDaSilva Center of Ebstein Anomaly, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Despite the clinical benefits of the cone operation for Ebstein's anomaly, significant right ventricular (RV) dysfunction is frequently seen immediately after the procedure and if persistent may portend worse long-term outcomes. In this study we sought to evaluate the predictors of RV dysfunction after the cone operation using preoperative CMR. Methods: This was a retrospective review of 26 consecutive patients who had the cone operation. Patients with significant RV dysfunction (RVD), defined as moderate or severe dysfunction by discharge echocardiogram, were compared to patients with no or mild dysfunction (no RVD). Results: The median age at the operation was 12.2 years (interquartile range (IQR): 4.9-31.7 years). Eighteen patients (69%) had RVD. Patients with RVD had worse preoperative RV ejection fraction (36 ​± ​15 vs 49 ​± ​11%, p ​= ​0.02) and a larger cardiothoracic (CT) index (44 ​± ​8 vs 37 ​± ​6, p ​= ​0.03). The tricuspid valve was more severely abnormal in the RVD group with higher rotational angle (45 ​± ​17 vs 23 ​± ​10°, 0.03) and higher displacement index (39 ​± ​18 vs 23 ​± ​12%, p ​= ​0.02). RVD associated with a higher vasoactive inotropic score (P ​< ​0.01) and a trend towards a longer intensive care stay (p ​= ​0.07). Conclusion: RVD is common after the cone operation and associated with higher need for postoperative inotropes. Predictors include lower preoperative RV ejection fraction, a more dilated heart and more severe tricuspid valve abnormality. Preoperative CMR is an important tool in preoperative assessment and helps predict RVD.

Indexed as

Adults with congenital heart diseaseCardiac MRICongenital heart diseaseEbsteinTricuspid valve

Identifiers

PMID39712277
PMCPMC11658122

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.