ArticleFrontiers in medicine2024
Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio associated with psoriasis: a cross-sectional study.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Integrating multi-source data and machine learning to Decipher the psoriasis-COPD comorbidity.Clinical and experimental medicine · 2026Article
- Remnant cholesterol and lipid ratios predict the relapse of neuromyelitis optica spectrum disorder.Lipids in health and disease · 2026Article
- Life's Crucial 9 and psoriasis: a mediation analysis of systemic inflammation response index using NHANES cohort data.Frontiers in immunology · 2025Article
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Authors and funding
4 authors.
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Abstract
Objective: Individuals with psoriasis face significant physiological and psychological burdens, and their compliance and satisfaction with medication regimens are alarmingly low. In recent years, the comorbidity of psoriasis has become a research focus. This study aims to explore the potential correlation between psoriasis and the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR). Methods: Data from 17,941 participants of the National Health and Nutrition Examination Survey (NHANES) spanning two intervals, 2003-2006 and 2009-2014, served as the foundation for this analysis. We used weighted logistic regression, stratified analysis, and restricted cubic spline (RCS) curve fitting to validate potential associations between NHHR and psoriasis risk. Results: In this investigation, the analysis of three different models highlighted elevated levels of the NHHR as a consistent risk factor for psoriasis. After adjusting for potential confounders, a positive correlation was observed between NHHR and the prevalence of psoriasis (OR = 1.08, 95% CI: 1.01, 1.15, Conclusion: Statistical analysis confirms a significant correlation between the NHHR and the development of psoriasis, suggesting that NHHR may serve as a novel marker for predicting psoriasis risk. This correlation also provides insights for early health management strategies.
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