Evidence map›Paper›PMID 39712032›Full record

ArticleFrontiers in immunology2024

Rituximab-IgG2 is a phagocytic enhancer in antibody-based immunotherapy of B-cell lymphoma by altering CD47 expression.

Oanh T P Nguyen, Sandra Lara, Giovanni Ferro, Matthias Peipp, Sandra Kleinau

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oanh T P NguyenDepartment of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.
Sandra LaraDepartment of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.
Giovanni FerroDepartment of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.
Matthias PeippDivision of Antibody-Based Immunotherapy, University Hospital Schleswig-Holstein, Kiel, Germany.
Sandra KleinauDepartment of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody-dependent cellular phagocytosis (ADCP) by monocytes and macrophages contributes significantly to the efficacy of many therapeutic monoclonal antibodies (mAbs), including anti-CD20 rituximab (RTX) targeting CD20

Indexed as

CD47 AntigenImmunoglobulin GLymphoma, B-CellPhagocytosisRituximabAntineoplastic Agents, ImmunologicalApoptosisCell Line, TumorHumansImmunotherapyAntineoplastic Agents, ImmunologicalCD47 AntigenCD47 protein, humanImmunoglobulin GRituximabanti-CD20 antibodyapoptosiscancer immunotherapyCD47monocytephagocytosisrituximab

Identifiers

PMID39712032
PMCPMC11659266

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.