Evidence map›Paper›PMID 39711799›Full record

SynthesisFrontiers in veterinary science2024

Golden era of radiosensitizers.

Jana Cizkova, Ondrej Jan Dolezal, Vojtech Buchta, Jan Pospichal, Vit Blanar, Zuzana Sinkorova, Anna Carrillo

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Lanthanide Nanotheranostics in Radiotherapy.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jana Cizkova *Department of Radiobiology, Military Faculty of Medicine, University of Defence, Hradec Kralove, Czechia.
Ondrej Jan DolezalDepartment of Radiobiology, Military Faculty of Medicine, University of Defence, Hradec Kralove, Czechia.
Vojtech BuchtaDepartment of Clinical Subspecialties, Faculty of Health Studies, University of Pardubice, Pardubice, Czechia.
Jan PospichalDepartment of Clinical Subspecialties, Faculty of Health Studies, University of Pardubice, Pardubice, Czechia.
Vit BlanarDepartment of Nursing, Faculty of Health Studies, University of Pardubice, Pardubice, Czechia.
Zuzana SinkorovaDepartment of Radiobiology, Military Faculty of Medicine, University of Defence, Hradec Kralove, Czechia.
Anna Carrillo *Department of Radiobiology, Military Faculty of Medicine, University of Defence, Hradec Kralove, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The past 30 years have brought undeniable progress in medicine, biology, physics, and research. Knowledge of the nature of the human body, diseases, and disorders has been constantly improving, and the same is true regarding their treatment and diagnosis. One of the greatest advances in recent years has been the introduction of nanoparticles (NPs) into medicine. NPs refer to a material at a nanometer scale (0.1-100 nm) with features (specific physical, chemical, and biological properties) that are broadly and increasingly used in the medical field. Their applications in cancer treatment and radiotherapy seem particularly attractive. In this field, inorganic/metal NPs with high atomic number Z have been employed mainly due to their ability to enhance ionizing radiation's photoelectric and Compton effects and thereby increase conventional radiation therapy's efficacy. The improvement NPs enable relates to their enhanced permeation ability and longer retention effect in tumor cells, capacity to reduce toxicity of commercially available cancer drugs through advanced NPs drug delivery systems, radiation sensitizers of tumors, or enhancers of radiation doses to tumors. Advanced options according to size, core, and surface modification allow even such multimodal approaches in therapy as nanotheranostics or combined treatments. The current state of knowledge emphasizes the role of gold nanoparticles (AuNPs) in sensitizing tumors to radiation. We have reviewed AuNPs and their radiosensitizing power during radiation treatment. Our results are divided into groups based on AuNPs' surface modification and/or core structure design. This study provides a complete summary of the

Indexed as

gold nanoparticlesin vivoradiosensitizersradiotherapytumor sensitizing

Identifiers

PMID39711799
PMCPMC11659289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.