Evidence map›Paper›PMID 39711728›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Connectome-based symptom mapping and

Patricia Segura, Marco Pagani, Somer L Bishop, Phoebe Thomson, Stanley Colcombe, Ting Xu, Zekiel Z Factor, Emily C Hector, So Hyun Kim, Michael V Lombardo and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Patricia SeguraChild Mind Institute, New York, NY, USA.
Marco PaganiChild Mind Institute, New York, NY, USA.
Somer L BishopDepartment of Psychiatry and Behavioral Sciences and Weill Institute for Neurosciences, University of California, San Francisco, California, USA.
Phoebe ThomsonChild Mind Institute, New York, NY, USA.
Stanley ColcombeNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Ting XuChild Mind Institute, New York, NY, USA.
Zekiel Z FactorChild Mind Institute, New York, NY, USA.
Emily C HectorDepartment of Statistics, North Carolina State University, Raleigh, North Carolina, USA.
So Hyun KimSchool of Psychology, Korea University, Seoul, South Korea.
Michael V LombardoLaboratory for Autism and Neurodevelopmental Disorders Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, 38068, Italy.
Alessandro GozziFunctional Neuroimaging Laboratory, Center for Neuroscience and Cognitive systems, Istituto Italiano di Tecnologia, Rovereto, Italy.
Xavier F CastellanosNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Catherine LordSemel Institute of Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Michael P MilhamChild Mind Institute, New York, NY, USA.
Adriana Di MartinoChild Mind Institute, New York, NY, USA.

Funding

Predicting Heterogeneous Neurodevelopmental Outcomes in School-age Children with Early Caregiving AdversitiesR01MH091864 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MILHAM, MICHAEL PETER, TOTTENHAM, NIM · 2010 to 2022
$5.1M
Neuronal Correlates of Autistic Traits in ADHD and AutismR01MH105506 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DI MARTINO, ADRIANA · 2015 to 2019
$3.7M
Reproducible imaging-based brain growth charts for psychiatryR01MH120482 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI MILHAM, MICHAEL PETER, SATTERTHWAITE, THEODORE · 2019 to 2023
$3.5M
Neural signatures of outcome in preschoolers with autismR01MH115363 · NIMH · CHILD MIND INSTITUTE, INC. · PI DI MARTINO, ADRIANA · 2018 to 2023
$3.5M
NIMH NIH HHS R01 MH091864NIMH NIH HHS R01 MH105506NIMH NIH HHS R01 MH115363NIMH NIH HHS R01 MH120482
6 · The paper itself

Abstract

Clinical, neuroimaging and genomics evidence have increasingly underscored a degree of overlap between autism and attention-deficit/hyperactivity disorder (ADHD). This study explores the specific contribution of their core symptoms to shared biology in a sample of N=166 verbal children (6-12 years) with rigorously-established primary diagnoses of either autism or ADHD (without autism). We investigated the associations between inter-individual differences in clinician-based dimensional measures of autism and ADHD symptoms and whole-brain low motion intrinsic functional connectivity (iFC). Additionally, we explored their linked gene expression patterns

Identifiers

PMID39711728
PMCPMC11661353

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.