Evidence map›Paper›PMID 39711716›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Genomic Epidemiology of 2023-2024 Oropouche Outbreak in Iquitos, Peru reveals independent origin from a concurrent outbreak in Brazil.

Maribel Paredes Olortegui, Francesca Schiaffino, Pablo Peñataro Yori, Josh M Colston, Valentino Shapiama Lopez, Tackeshy Pinedo Vasquez, Paul F Garcia Bardales, Thomas G Flynn, Cesar Ramal-Asayag, Holley R Hughes and 10 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Maribel Paredes OlorteguiAsociación Benéfica Prisma, Iquitos, Peru.
Francesca SchiaffinoDivision of Infectious Diseases and International Health, School of Medicine, University of Virginia, VA, USA.ORCID 0000-0002-5796-5116
Pablo Peñataro YoriAsociación Benéfica Prisma, Iquitos, Peru.
Josh M ColstonDivision of Infectious Diseases and International Health, School of Medicine, University of Virginia, VA, USA.ORCID 0000-0003-4567-5813
Valentino Shapiama LopezAsociación Benéfica Prisma, Iquitos, Peru.
Tackeshy Pinedo VasquezAsociación Benéfica Prisma, Iquitos, Peru.
Paul F Garcia BardalesAsociación Benéfica Prisma, Iquitos, Peru.
Thomas G FlynnDivision of Infectious Diseases and International Health, School of Medicine, University of Virginia, VA, USA.ORCID 0000-0002-9262-9601
Cesar Ramal-AsayagSchool of Human Medicine, Universidad Nacional de la Amazonia Peruana, Iquitos, Peru.
Holley R HughesArboviral Diseases Branch, Division of Vector-borne Diseases, US Center for Disease Control and Prevention, Fort Collins, CO, USA.ORCID 0000-0003-1380-8263
Emily DavisArboviral Diseases Branch, Division of Vector-borne Diseases, US Center for Disease Control and Prevention, Fort Collins, CO, USA.
Brandy J RussellArboviral Diseases Branch, Division of Vector-borne Diseases, US Center for Disease Control and Prevention, Fort Collins, CO, USA.ORCID 0000-0003-0408-999X
Aaron C BraultArboviral Diseases Branch, Division of Vector-borne Diseases, US Center for Disease Control and Prevention, Fort Collins, CO, USA.ORCID 0000-0001-5801-3021
Yuri Alfonso Alegre PalominoGerencia Regional de Salud, Gobierno Regional de Loreto, Loreto, Peru.
Cesar MunaycoCentro Nacional de Epidemiologia, Prevención y Control de Enfermedades, Ministerio de Salud, Peru.
Jie LiuSchool of Public Health, Qingdao University, Qingdao, China.
Eric HouptDivision of Infectious Diseases and International Health, School of Medicine, University of Virginia, VA, USA.ORCID 0000-0003-1085-1354
Kerry K CooperSchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ.ORCID 0000-0003-4541-1324
Craig T ParkerAgricultural Research Service, U.S. Department of Agriculture, Produce Safety and Microbiology Research Unit, Albany, CA, USA.ORCID 0000-0002-7719-8882
Margaret N KosekAsociación Benéfica Prisma, Iquitos, Peru.ORCID 0000-0001-6340-4852

Funding

INFECTIOUS DISEASES TRAINING PROGRAMT32AI007046 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Alison K Criss, William A Petri · 1985 to 2026
$15.3M
Enabling Infectious Disease Research Capacity in the Peruvian AmazonD43TW010913 · FIC · UNIVERSITY OF VIRGINIA · PI Margaret N Kosek, MARIBEL PAREDES OLORTEGUI · 2018 to 2026
$2.8M
Genomic Epidemiology of Campylobacter in Poultry to Enable the Effective Control of Human Campylobacteriosis in a Middle Income CountryK43TW012298 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI Francesca Schiaffino · 2022 to 2026
$811k
The Planetary Child Health Observatory: an interdisciplinary research initiative and web-based dashboard for mapping enteric infectious diseases and their risk factors and interventions in LMICsK01AI168493 · NIAID · UNIVERSITY OF VIRGINIA · PI Josh M Colston · 2023 to 2026
$519k
CGH CDC HHS U01 GH002270FIC NIH HHS D43 TW010913FIC NIH HHS K43 TW012298NIAID NIH HHS K01 AI168493NIAID NIH HHS T32 AI007046
6 · The paper itself

Abstract

Oropouche virus is an arbovirus endemic to the Americas. Periodic outbreaks have occurred since its description in 1955. In late 2023, an outbreak occurred in Peru, centered in and around Iquitos in the Eastern Peruvian Amazon. An existing acute febrile illness (AFI) surveillance program was able to document its emergence and characterize arthralgia and dysuria and the absence of diarrhea as distinctive clinical features of Oropouche virus-associated febrile illness relative to other causes of AFI. Sequencing of isolates from the outbreak demonstrated that strains from this region were distinct from those causing disease in Brazil, despite the large-scale movement of people along the Amazon corridor, but highly similar to strains from Colombia and Ecuador. Our findings suggest that the current outbreak in South America is fundamentally multifocal in origin and not the result of geographic spread from Brazil, which experienced an outbreak between 2022 and 2024.

Indexed as

acute febrile illnessarbovirusorthobunyavirus

Identifiers

PMID39711716
PMCPMC11661442

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.