Evidence map›Paper›PMID 39711675›Full record

ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2024

Predictors of Recurrence After Curative Surgery for Stage I Colon Cancer: Retrospective Cohort Analysis of the Italian Society of Surgical Oncology Colorectal Cancer Network Collaborative Group.

Giulia Turri, Luigi Martinelli, Daniela Rega, Nicolò Tamini, Lucia Paiano, Simona Deidda, QuocRiccardo Bao, Laura Lorenzon, Raffaele De Luca, Caterina Foppa and 40 more

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Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Giulia TurriFrom the Chirurgia Generale ed Epatobiliare, Azienda Ospedaliera Universitaria Integrata di Verona, Università degli Studi di Verona, Verona, Italy.
Luigi MartinelliDepartment of Diagnostic and Public Health, University of Verona, Verona, Italy.
Daniela RegaColorectal Surgical Oncology, Abdominal Oncology Department, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione G. Pascale" IRCSS, Naples, Italy.
Nicolò TaminiChirurgia Generale, IRCCS San Gerardo Monza, Università Milano Bicocca, Milano, Italy.
Lucia PaianoUCO Clinica Chirurgica, Università di Trieste, Trieste, Italy.
Simona DeiddaUOC Chirurgia Coloproctologica, AOU Cagliari, Cagliari, Italy.
QuocRiccardo BaoChirurgia Generale 3, Azienda Ospedaliera Universitaria Integrata di Padova, Padova, Italy.
Laura LorenzonUOC Chirurgia Generale 1, Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Roma, Italy.
Raffaele De LucaDepartment of Surgical Oncology, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Caterina FoppaDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Valentina MariChirurgia Generale, Ospedale Santa Maria della Misericordia, Rovigo, Italy.
Giovanni TaffurelliChirurgia Colorettale, Ospedale Santa Maria delle Croci, Ravenna, Italy.
Arcangelo PicciarielloDepartment of Experimental Medicine, University of Salento, Lecce, Italy.
Patrizia MarsanicS.C. Chirurgia, Ospedale E. Agnelli, ASL TO 3, Presidio Pinerolo, Italy.
Leandro SiragusaMinimally Invasive and Gastrointestinal Surgery Unit, Department of General Surgery, University of Rome Tor Vergata, Rome, Italy.
Francesco BagoliniChirurgia 1, Ospedale di Cona, Azienda Ospedaliera Universitaria Integrata di Ferrara, Ferrara, Italy.
Riccardo NascimbeniClinica Chirurgica, Dipartimento di Scienze Cliniche e Sperimentali, Università degli Studi di Brescia, Brescia, Italy.
Gianluca RizzoUOC Chirurgia Digestiva e del Colon-Retto - Ospedale Isola Tiberina Gemelli Isola, Roma, Italy.
Sara VertaldiChirurgia Endoscopica, AOUI Federico II Napoli, Napoli, Italy.
Michele ZuoloAPSS, Azienda Provinciale per i Servizi Sanitari, UO di Chirurgia Generale, Ospedale Valli del Noce, Trento, Italy.
Giorgio BianchiUnit of Digestive and HPB Surgery, Henri Mordor University Hospital, Paris, France.
Lisa Marie RoratoChirurgia d'Urgenza e PS 3, AOU Città della Salute e della Scienza, Torino, Italy.
Rossella ReddavidDivision of Surgical Oncology and Digestive Surgery, Department of Oncology, University of Turin, San Luigi University Hospital, Turin, Italy.
Gaetano GalloUnità di Chirurgia Colorettale, Clinica Santa Rita, Vercelli, Italy.
Lorenzo CrepazChirurgia Generale e Mininvasiva, Ospedale San Camillo, Trento, Italy.
Alberto Di LeoChirurgia Generale e Mininvasiva, Ospedale San Camillo, Trento, Italy.
Mario TrompettoUnità di Chirurgia Colorettale, Clinica Santa Rita, Vercelli, Italy.
Enrico PotenzaDivision of Surgical Oncology and Digestive Surgery, Department of Oncology, University of Turin, San Luigi University Hospital, Turin, Italy.
Mauro SantarelliChirurgia d'Urgenza e PS 3, AOU Città della Salute e della Scienza, Torino, Italy.
Nicola de'AngelisUnit of Digestive and HPB Surgery, Henri Mordor University Hospital, Paris, France.
Francesco CiarleglioAPSS, Azienda Provinciale per i Servizi Sanitari, UO di Chirurgia Generale, Ospedale Valli del Noce, Trento, Italy.
Marco MiloneChirurgia Endoscopica, AOUI Federico II Napoli, Napoli, Italy.
Claudio CocoChirurgia Generale 2, Fondazione Policlinico Universitario "A.Gemelli", IRCCS Roma, Italy.
Guido Alberto TiberioClinica Chirurgica, Dipartimento di Scienze Cliniche e Sperimentali, Università degli Studi di Brescia, Brescia, Italy.
Gabriele AnaniaChirurgia 1, Ospedale di Cona, Azienda Ospedaliera Universitaria Integrata di Ferrara, Ferrara, Italy.
Giuseppe S SicaMinimally Invasive and Gastrointestinal Surgery Unit, Department of General Surgery, University of Rome Tor Vergata, Rome, Italy.
Andrea MuratoreS.C. Chirurgia, Ospedale E. Agnelli, ASL TO 3, Presidio Pinerolo, Italy.
Donato Francesco AltomareDipartimento di Medicina di Precisione e Rigenerativa e Polo Jonico (DiMePRE-J), Università degli Studi Aldo Moro di Bari, Bari, Italy.
Isacco MontroniChirurgia Colorettale, Ospedale Santa Maria delle Croci, Ravenna, Italy.
Maurizio De LucaChirurgia Generale, Ospedale Santa Maria della Misericordia, Rovigo, Italy.
Antonino SpinelliDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Michele SimoneDepartment of Surgical Oncology, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Roberto PersianiUOC Chirurgia Generale 1, Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Roma, Italy.
Gaya SpolveratoChirurgia Generale 3, Azienda Ospedaliera Universitaria Integrata di Padova, Padova, Italy.
Angelo RestivoUOC Chirurgia Coloproctologica, AOU Cagliari, Cagliari, Italy.
Nicolò de ManziniUCO Clinica Chirurgica, Università di Trieste, Trieste, Italy.
Marco BragaChirurgia Generale, IRCCS San Gerardo Monza, Università Milano Bicocca, Milano, Italy.
Paolo DelrioColorectal Surgical Oncology, Abdominal Oncology Department, Istituto Nazionale per lo Studio e la Cura dei Tumori, "Fondazione G. Pascale" IRCSS, Naples, Italy.
Giuseppe VerlatoDepartment of Diagnostic and Public Health, University of Verona, Verona, Italy.
Corrado PedrazzaniFrom the Chirurgia Generale ed Epatobiliare, Azienda Ospedaliera Universitaria Integrata di Verona, Università degli Studi di Verona, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study is to provide solid evidence to update the management of stage I colon cancer (CC) after surgery. Background: Given the low risk of recurrence of stage I CC, some international guidelines do not recommend intensive follow-up after surgery. However, data on the actual incidence, risk factors, and site of recurrences are scarce. Methods: This is a retrospective multicenter cohort study considering patients who underwent surgery at 25 Italian centers between 2010 and 2019, with a minimum follow-up of 24 months. A total of 1883 consecutive adult patients with stage I CC treated with curative surgery were considered, and 1611 fulfilled the inclusion criteria. The primary outcome was the rate of recurrence. Secondary outcomes included survival and risk factors for recurrence. Results: Eighty patients developed cancer recurrence (5.0%), of which 90% was systemic relapse. The event was more frequent in pT2 (6.0% vs 3.2%, Conclusions: This study showed that a not negligible rate of stage I CC recur after curative surgery. Most relapses occur at a single site within the first 3 years after surgery. This evidence could be used to optimize postoperative follow-up.

Indexed as

colon cancerfollow-upprognosisrecurrence, stage I

Identifiers

PMID39711675
PMCPMC11661724

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