Evidence map›Paper›PMID 39711565›Full record

ArticleResearch square2024

BMIgap: a new tool to quantify transdiagnostic brain signatures of current and future weight.

Nikolaos Koutsouleris, Adyasha Tejaswi Khuntia, David Popovic, Elif Sarisik, Madalina O Buciuman, Mads L Pedersen, Lars T Westlye, Ole Andreassen, Andreas Meyer-Lindenberg, Joseph Kambeitz and 12 more

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Nikolaos KoutsoulerisLudwig-Maximilians-University.ORCID 0000-0001-6825-6262
Adyasha Tejaswi KhuntiaLudwig-Maximilian-University.
David PopovicMax-Planck-Institute of Psychiatry.ORCID 0000-0002-2367-9437
Elif SarisikLudwig-Maximilians-University.
Madalina O BuciumanLudwig-Maximilians-University.
Mads L PedersenUniversity of Oslo.
Lars T WestlyeUniversity of Oslo.ORCID 0000-0001-8644-956X
Ole AndreassenOslo University Hospital & Institute of Clinical Medicine, University of Oslo.ORCID 0000-0002-4461-3568
Andreas Meyer-LindenbergCentral Institute of Mental Health, Mannheim.
Joseph KambeitzFaculty of Medicine and University Hospital University of Cologne Cologne.ORCID 0000-0002-8988-3959
Raimo SalokangasDepartment of Psychiatry, University of Turku.
Jarmo HietalaDepartment of Psychiatry, University of Turku and Turku University Hospital, Finland.
Alessandro BertolinoDepartment of Translational Biomedicine and Neuroscience, University of Bari "Aldo Moro", Bari, Italy.
Stefan BorgwardtUniversity of Lübeck.ORCID 0000-0002-5792-3987
Paolo BrambillaUniversity of Milan.
Rachel UpthegroveUniversity of Birmingham.ORCID 0000-0001-8204-5103
Stephen WoodUniversity of Melbourne.
Rebekka LencerDepartment of Psychiatry and Psychotherapy and Center for Brain, Behaviour and Metabolism, University of Lübeck.
Eva MeisenzahlKliniken der Heinrich-Heine-Universität.
Peter FalkaiLudwig Maximilians University Munich.
Emanuel SchwarzCentral Institute of Mental Health.ORCID 0000-0002-0261-5063
Ariane WiegandLudwig-Maximilian-University.

Funding

ProNET: Psychosis-Risk Outcomes NetworkU01MH124639 · NIMH · YALE UNIVERSITY · PI CARRIE E BEARDEN, JOHN M KANE · 2020 to 2026
$81.2M
NIMH NIH HHS U01 MH124639Wellcome Trust
6 · The paper itself

Abstract

Understanding the neurobiological underpinnings of weight gain could reduce excess mortality and improve long-term trajectories of psychiatric disorders. We used support-vector machines and whole-brain voxel-wise grey matter volume to generate and validate a BMI predictor in healthy individuals (N = 1504) and applied it to individuals with schizophrenia (SCZ,N = 146), clinical high-risk states for psychosis (CHR,N = 213) and recent-onset depression (ROD,N = 200). We computed BMIgap (BMI

Indexed as

BMIgrey matter volumemachine learningmajor depressive disorderschizophrenia

Identifiers

PMID39711565
PMCPMC11661285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.