Evidence map›Paper›PMID 39711558›Full record

ArticleResearch square2024

Structure guided functional analysis of the S. cerevisiae Mre11 complex.

John Petrini, Marcel Hohl, You Yu, Vitaly Kuryavyi, Dinshaw Patel

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

John PetriniMemorial Sloan Kettering Cancer Center.ORCID 0000-0001-5102-5679
Marcel HohlMemorial Sloan-Kettering.
You YuZhejiang University School of Medicine.
Vitaly KuryavyiMSKCC.ORCID 0000-0003-3938-6652
Dinshaw PatelMemorial Sloan Kettering Cancer Center.ORCID 0000-0002-9779-7778

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
DNA Damage & DNA Replication: a Complex RelationshipR35GM136278 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI John HJ Petrini · 2020 to 2026
$5.5M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R35 GM136278
6 · The paper itself

Abstract

The Mre11 complex comprises Mre11, Rad50 and Nbs1 (Xrs2 in

Indexed as

coiled coilCryo-EMDNA repairdouble strand breakhookMre11 complexRad50

Identifiers

PMID39711558
PMCPMC11661359

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.