Evidence map›Paper›PMID 39711257›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2025

Evaluation of the Biocompatibility of Poly(benzimidazobenzophenanthroline)(BBL) Polymer Films with Living Cells.

Claudia Latte Bovio, Paola Campione, Han-Yan Wu, Qifan Li, Ana De La Fuente Durán, Alberto Salleo, Simone Fabiano, Grazia Maria Lucia Messina, Francesca Santoro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. An organic artificial cardiomyocyte.Nature communications · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Claudia Latte BovioTissue Electronics, Istituto Italiano di Tecnologia, Naples, 80125, Italy.ORCID 0000-0002-2064-4570
Paola CampioneLaboratory for Molecular Surface and Nanotechnology (LAMSUN), Department of Chemical Sciences, University of Catania. and CSGI, Viale A. Doria, 6, Catania, 95125, Italy.ORCID 0009-0004-1756-028X
Han-Yan WuLaboratory of Organic Electronics Department of Science and Technology, Linköping University, Norrköping, SE-60174, Sweden.
Qifan LiLaboratory of Organic Electronics Department of Science and Technology, Linköping University, Norrköping, SE-60174, Sweden.
Ana De La Fuente DuránDepartment of Materials Science and Engineering, Stanford University, Stanford, CA, 94305, USA.
Alberto SalleoDepartment of Materials Science and Engineering, Stanford University, Stanford, CA, 94305, USA.
Simone FabianoLaboratory of Organic Electronics Department of Science and Technology, Linköping University, Norrköping, SE-60174, Sweden.
Grazia Maria Lucia MessinaLaboratory for Molecular Surface and Nanotechnology (LAMSUN), Department of Chemical Sciences, University of Catania. and CSGI, Viale A. Doria, 6, Catania, 95125, Italy.
Francesca SantoroTissue Electronics, Istituto Italiano di Tecnologia, Naples, 80125, Italy.ORCID 0000-0001-7323-9504

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of organic electronic materials with biological systems to monitor, interface with, and regulate physiological processes is a key area in the field of bioelectronics. Central to this advancement is the development of cell-chip coupling, where materials engineering plays a critical role in enhancing biointerfacing capabilities. Conductive polymers have proven particularly useful in cell interfacing applications due to their favorable biophysical and chemical properties. However, n-type conductive polymers remain underexplored, primarily due to their limited long-term stability. In this study, it is demonstrated that the conductive polymer poly(benzimidazobenzophenanthroline) (BBL), commonly used in organic electronic devices, can effectively support neuronal cell viability and spreading, both as a bare cell culture material and when coated with exracellular matrix proteins. This work provides a preliminary validation of BBL's potential for future integration into bioelectronic devices and in biointerfacing.

Indexed as

Biocompatible MaterialsMaterials TestingPhenanthrolinesPolymersAnimalsCell SurvivalRatsBiocompatible MaterialsPhenanthrolinesPolymersBBLcell‐chip couplingin vitro biocompatibilityneuronal cellsorganic bioelectronics

Identifiers

PMID39711257
PMCPMC11798344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.