ArticleBrain and behavior2024
Relationship of Neutrophil Percentage-to-Albumin Ratio With Stroke: Evidence From NHANES 1999-2020.
Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed.
- High neutrophil-to-albumin ratio signals severe prognosis in LVO stroke-data from an EICU cohort.Frontiers in medicine · 2026Article
- Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors.Frontiers in aging neuroscience · 2025Article
- Neutrophil Percentage-to-Albumin Ratio as a Prognostic Marker for Mortality in Ischemic Stroke Patients.International journal of medical sciences · 2025Article
- Study on the link between neutrophil percentage to albumin ratio and acute kidney injury in severe ischemic stroke patients during hospitalization.Frontiers in neurology · 2025Article
- Renal function mediates the association between neutrophil percentage-to-albumin ratio and survival in cancer survivors: a large cross-sectional study.Frontiers in oncology · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveThe objective of this research is to examine the association between neutrophil percentage-to-albumin ratio (NPAR) and stroke, providing a reference for the prevention and prognosis of clinical stroke.
methodThe study included 56,566 participants from the National Health and Nutrition Examination Survey (NHANES) to explore the association between NPAR and stroke using logistic regression and restricted cubic splines. Upon identifying the nonlinear relationship, inflection points were calculated using recursive algorithms and two-stage linear regression models. Stratified analyses and interaction tests examined variations across population groups.
resultsAfter adjusting for confounders, NPAR was positively associated with stroke (OR: 1.09, 95% CI: 1.05-1.12). Restricted cubic spline analysis indicated a nonlinear trend. Beyond the inflection point, the increasing trend of stroke incidence with higher NPAR levels began to slow down. This relationship remained nonlinear in males but was linear in females.
conclusionThis study revealed a nonlinear positive association between NPAR and stroke, with higher NPAR increasing the risk of stroke.
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Registered trials
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