Evidence map›Paper›PMID 39710924›Full record

ReviewInfectious disorders drug targets2025

Intensification of Invasive Fungal Infections and Exploration of Effective Antifungal Drug Delivery Formulations: A Detailed Review.

Shrikant Mahesh Sharma, Rupali Sharma, Pankaj Chandrateya

Abstract readReview
PubMed Publisher
In one paragraph

Review in Infectious disorders drug targets, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shrikant Mahesh SharmaDepartment of Pharmaceutics, Amity Institute of Pharmacy, Amity University Haryana, Manesar, Gurugram, 122413, India.
Rupali SharmaDepartment of Pharmaceutics, Amity Institute of Pharmacy, Amity University Haryana, Manesar, Gurugram, 122413, India.
Pankaj ChandrateyaIndeus Life Sciences, Maharashtra, Mumbai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive fungal infections (IFIs) pose a significant global health threat, particularly among immunocompromised individuals. These infections can lead to severe illness and death, placing a significant financial burden on healthcare systems. Fungi were not previously considered a substantial risk to human health, but this perception changed with the rise of the HIV epidemic. The emergence of drug-resistant fungal strains further complicates the management of these infections, highlighting the urgent need for effective antifungal therapies. Innovative approaches in antifungal drug delivery formulations. This article explores the role of effective antifungal drug delivery formulations in combating the rise of IFIs. These formulations, ranging from lipid-based systems like liposomes and lipid emulsions to polymeric nanoparticles and microparticles, offer several advantages over conventional drug delivery methods. Optimizing these formulations may improve drug efficacy, reduce the risk of drug resistance, and enhance patient outcomes. Furthermore, advancements in nanotechnology and targeted drug delivery systems hold promise in overcoming existing limitations and expanding the scope of antifungal therapies.

Indexed as

Antifungal AgentsDrug Delivery SystemsInvasive Fungal InfectionsDrug Resistance, FungalHumansImmunocompromised HostLiposomesNanoparticlesAntifungal AgentsLiposomesDrug resistanceeconomic burdenfungal infection preventionglobal health threathealthcare.immunocompromised individuals

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.