Evidence map›Paper›PMID 39710798›Full record

ArticleMikrochimica acta2024

An electrochemical aptasensor for the detection of bisphenol A based on triple signal amplification assisted by gold nanoparticles, hemin/G-quadruplex DNAzyme, and exonuclease I.

Yanhong Liu, Xueqin Xu

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yanhong LiuKey Laboratory for Analytical Science of Food Safety and Biology, MOE, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Xueqin XuKey Laboratory for Analytical Science of Food Safety and Biology, MOE, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, 350108, China. xxq@fzu.edu.cn.

Funding

National Natural Science Foundation of China 21475024
6 · The paper itself

Abstract

A triple signal amplified electrochemical aptasensor for the detection of bisphenol A (BPA) was developed for the first time based on gold nanoparticles (AuNPs), hemin/G-quadruplex DNAzyme, and exonuclease I (Exo I) assisted amplification strategies. The BPA aptamer (Apt) hybridized with the capture probe (CP) was fixed on the gold electrode (GE) to form the double-stranded DNA (dsDNA) structure. When BPA was present, the Apt was detached from the GE surface by specific recognition between the BPA and Apt, forming BPA-Apt complexes in solution. The complexes could be selectively digested by Exo I, releasing BPA to participate in the cycle for binding to other Apt in dsDNA. The hybridization of the CP and auxiliary DNA (aDNA) within the detect probe DNA (dpDNA)-AuNP-aDNA nanocomplex allowed the nanocomplex to connect to the GE surface. The dpDNA interacted with K

Indexed as

Aptamers, NucleotideBenzhydryl CompoundsBiosensing TechniquesDNA, CatalyticElectrochemical TechniquesExodeoxyribonucleasesGoldG-QuadruplexesHeminLimit of DetectionMetal NanoparticlesPhenolsBisphenol A CompoundsWater Pollutants, ChemicalAptamers, NucleotideBenzhydryl Compoundsbisphenol ABisphenol A CompoundsDNA, Catalyticexodeoxyribonuclease IExodeoxyribonucleasesGoldHeminPhenolsWater Pollutants, ChemicalBisphenol ADifferential pulse voltammetryElectrochemical aptasensorExonuclease IGold nanoparticlesHemin/G-quadruplex DNAzymeSignal amplification

Identifiers

PMID39710798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.