Evidence map›Paper›PMID 39710783›Full record

ArticleAnalytical and bioanalytical chemistry2025

Reliable and precise Zn isotopic analysis of biological matrices using a fully automated dual-column purification procedure.

Anika Retzmann, Kerri A Miller, Fwziah Ali Abdalali Mohamed, Michael E Wieser

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anika RetzmannDepartment of Physics and Astronomy, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. anika.retzmann@ucalgary.ca.
Kerri A MillerArnie Charbonneau Cancer Institute, University of Calgary, 3280 Hospital Dr. NW, Calgary, AB, T2N 4Z6, Canada.
Fwziah Ali Abdalali MohamedDepartment of Physics and Astronomy, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada.
Michael E WieserDepartment of Physics and Astronomy, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada.

Funding

Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften Leopoldina Postdoc Scholarship (LPDS 2022-14)Natural Sciences and Engineering Research Council of Canada Discovery Grant
6 · The paper itself

Abstract

A fully automated dual-column purification procedure for Zn from biological samples, designed for subsequent Zn isotopic analysis, is presented that utilizes the prepFAST MC™ system (Elemental Scientific), DGA resin (TrisKem International), and TK201 resin (TrisKem International). The procedure developed enables the unattended processing of 20 samples per day and is characterized by low and reproduceable blanks (< 1.5 ng), no carry-over or memory effect, high reusability (> 50 times), high Zn yields 100.1% ± 5.3% (2 SD, N = 22), and strong robustness to matrix variations across biological samples (bone, liver, hair, blood). Additionally, Zn isotopic analysis using MC-ICP-MS showed no significant on-column fractionation. The measured δ

Indexed as

ZincZinc IsotopesAnimalsAutomationBone and BonesHairHumansLiverMass SpectrometryReproducibility of ResultsZincZinc IsotopesDGA resinIsotope metallomicsMC-ICP-MSPrepFAST MC™TK201 resinδ 66Zn

Identifiers

PMID39710783

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.