Evidence map›Paper›PMID 39710701›Full record

ArticleParasites & vectors2024

Symbiotic bacteria associated with entomopathogenic nematodes showed molluscicidal activity against Biomphalaria glabrata, an intermediate host of Schistosoma mansoni.

Jiranun Ardpairin, Chanakan Subkrasae, Abdulhakam Dumidae, Supawan Pansri, Chanatinat Homkaew, Wipanee Meesil, Tewarat Kumchantuek, Ittipon Phoungpetchara, Adler R Dillman, Coralie Pavesi and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasites & vectors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiranun ArdpairinDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Chanakan SubkrasaeDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Abdulhakam DumidaeDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Supawan PansriDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Chanatinat HomkaewDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Wipanee MeesilDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Tewarat KumchantuekDepartment of Anatomy, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Ittipon PhoungpetcharaDepartment of Anatomy, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Adler R DillmanDepartment of Nematology, University of California, Riverside, CA, 92521, USA.
Coralie PavesiMax-Planck-Institut für Terrestrische Mikrobiologie Abteilung Naturstoffe in organismischen Interaktionen, Karl-von-Frisch-Str. 10, 35043, Marburg, Germany.
Helge B BodeMax-Planck-Institut für Terrestrische Mikrobiologie Abteilung Naturstoffe in organismischen Interaktionen, Karl-von-Frisch-Str. 10, 35043, Marburg, Germany.
Sarunporn TandhavanantDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
Aunchalee ThanwisaiDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Apichat VittaDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand. apichatv@nu.ac.th.

Funding

Naresuan University (NU) and the National Science, Research and Innovation Fund (NSRF) R2567B034the National Research Council of Thailand PHD / 0086/2561
6 · The paper itself

Abstract

backgroundBiomphalaria glabrata acts as the intermediate host of schistosomes that causes human schistosomiasis. Symbiotic bacteria, Xenorhabdus and Photorhabdus associated with Steinernema and Heterorhabditis, produce secondary metabolites with several biological activities. Controlling B. glabrata is a potential strategy to limit the transmission of schistosomiasis. The aims of this study were to identify Xenorhabdus and Photorhabdus bacteria based on recA sequencing and evaluate their molluscicidal activity against B. glabrata snail.

resultsA total of 31 bacterial isolates belonging to Xenorhabdus (n = 19) and Photorhabdus (n = 12) (X. ehlersii, X. stockiae, X. indica, X. griffinae, P. luminescens, P. akhurstii, and P. laumondii subsp. laumondii were molecularly identified based on recA sequencing. Five isolates of bacterial extracts showed potential molluscicide, with 100% snail mortality. P. laumondii subsp. laumondii (bALN19.5_TH) showed the highest effectiveness with lethal concentration (LC) values of 54.52 µg/mL and 89.58 µg/mL for LC

conclusionsFive bacterial extracts showed good activity against B. glabrata, especially P. laumondii subsp. laumondii and X. stockiae, which produced virulent secondary metabolites resulting in the death of the snails. They also caused histopathological alterations in the foot, digestive glands, and hermaphrodite glands of the snails. This study suggests that extracts from these bacteria show promise as molluscicides for the control of B. glabrata.

Indexed as

BiomphalariaMolluscacidesSymbiosisAnimalsPhotorhabdusSchistosoma mansoniXenorhabdusMolluscacidesEntomopathogenic nematodeHistological alterationSchistosomeSnailSymbiotic bacteria

Identifiers

PMID39710701
PMCPMC11665110

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.