Evidence map›Paper›PMID 39710590›Full record

ArticleGut microbes2025

Maternal probiotic exposure enhances CD8 T cell protective neonatal immunity and modulates offspring metabolome to control influenza virus infection.

Clara Valentin, Patricia Brito Rodrigues, Marko Verce, Sandrine Delbauve, Léa La Palombara, Florine Demaret, Justine Allard, Isabelle Salmon, Patrice D Cani, Arnaud Köhler and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Clara ValentinInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Patricia Brito RodriguesMetabolism and Nutrition Research Group, Louvain Drug Research Institute, UCLouvain, Université Catholique de Louvain, Brussels, Belgium.
Marko VerceMetabolism and Nutrition Research Group, Louvain Drug Research Institute, UCLouvain, Université Catholique de Louvain, Brussels, Belgium.
Sandrine DelbauveInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Léa La PalombaraInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Florine DemaretInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Justine AllardDIAPath, Center for Microscopy and Molecular Imaging, Université Libre de Bruxelles, Gosselies, Belgium.
Isabelle SalmonDIAPath, Center for Microscopy and Molecular Imaging, Université Libre de Bruxelles, Gosselies, Belgium.
Patrice D CaniMetabolism and Nutrition Research Group, Louvain Drug Research Institute, UCLouvain, Université Catholique de Louvain, Brussels, Belgium.ORCID 0000-0003-2040-2448
Arnaud KöhlerInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Amandine EverardMetabolism and Nutrition Research Group, Louvain Drug Research Institute, UCLouvain, Université Catholique de Louvain, Brussels, Belgium.ORCID 0000-0001-8925-8144
Véronique FlamandInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maternal gut microbiota composition contributes to the status of the neonatal immune system and could influence the early life higher susceptibility to viral respiratory infections. Using a novel protocol of murine maternal probiotic supplementation, we report that perinatal exposure to

Indexed as

Animals, NewbornCD8-Positive T-LymphocytesGastrointestinal MicrobiomeMetabolomeOrthomyxoviridae InfectionsProbioticsAnimalsDendritic CellsFemaleInfluenza A virusInterferon-gammaLacticaseibacillus rhamnosusMiceMice, Inbred C57BLPregnancyInterferon-gammaBifidobacteriumCD8 T cellsearly lifeIAVLacticaseibacillus rhamnosusmemory response

Identifiers

PMID39710590
PMCPMC12931718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.