Evidence map›Paper›PMID 39710495›Full record

ArticleAlcohol, clinical & experimental research2025

A randomized controlled trial of Native CHOICES: Impact on alcohol-exposed pregnancy risk reduction among American Indian and Alaska Native women.

Jessica Hanson, Carolyn Noonan, Kyra Oziel, Karen Little Wounded, Serea Darnell, Robert Rosenman, Marcia O'Leary, Richard MacLehose, Michelle Sarche, Dedra Buchwald

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alcohol, clinical & experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. An economic analysis of Native CHOICES.Journal of substance use and addiction treatment · 2026
    Trial
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jessica HansonDepartment of Applied Human Sciences, University of Minnesota Duluth, Duluth, Minnesota, USA.ORCID https://orcid.org/0000-0001-8867-2300
Carolyn NoonanInstitute for Research and Education to Advance Community Health, Washington State University, Seattle, Washington, USA.
Kyra OzielInstitute for Research and Education to Advance Community Health, Washington State University, Seattle, Washington, USA.
Karen Little WoundedMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Serea DarnellMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Robert RosenmanSchool of Economic Sciences, Washington State University, Pullman, Washington, USA.
Marcia O'LearyMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Richard MacLehoseDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
Michelle SarcheUniversity of Colorado Anschutz Medical Campus, Colorado School of Public Health, Centers for American Indian and Alaska Native Health, Aurora, Colorado, USA.
Dedra BuchwaldDepartment of Neurological Surgery, UW Medicine, University of Washington, Seattle, Washington, USA.

Funding

Transition to RecoveryP60AA026112 · NIAAA · WASHINGTON STATE UNIVERSITY · PI Denise A Dillard, Michael G McDonell · 2018 to 2026
$10.7M
NIAAA NIH HHS P60 AA026112NIAAA NIH HHS P60AA026112
6 · The paper itself

Abstract

backgroundPrevention of alcohol-exposed pregnancy (AEP) involves reducing risky alcohol consumption among women at-risk for pregnancy, using effective contraception among women drinking at risky levels to prevent pregnancy, or both. This study presents the outcomes of a randomized controlled trial assessing the efficacy of Native CHOICES, a culturally tailored adaptation of the CHOICES intervention, among American Indian/Alaska Native (AI/AN) women.

methodsAI/AN women aged 18-44 who were at-risk for an AEP were randomly assigned in a 1:1 ratio to either the Native CHOICES intervention or a waitlist control group. Native CHOICES comprised two sessions of motivational interviewing and an elective contraception counseling session. Data were collected at baseline, and 6 weeks, 3 months, and 6 months postbaseline. Due to the pandemic, the intervention was at times delivered remotely.

resultsA total of 404 women participated: 199 in the control group and 205 in the intervention group. Sixty-seven percent of the intervention group received the intervention in-person, and 33% participated by telephone or video call. Sixty-four percent of women completed all follow-up visits. At the six-month follow-up, the intervention did not demonstrate a significant impact on AEP risk compared with the control arm when analyzing all the data (RR = 0.94; 95% confidence interval [CI]: 0.83-1.07). However, an exploratory subgroup analysis showed evidence of a reduction in AEP risk among participants who completed the study in-person before the COVID-19 pandemic (RR = 0.79; 95% CI: 0.63-0.98), which was not observed during or after the pandemic (RR = 1.06; 95% CI: 0.91-1.24).

conclusionsThe Native CHOICES intervention did not show evidence of effectiveness overall. However, exploratory analyses offer some evidence that the intervention was effective prior to the pandemic.

Indexed as

alcoholalcohol‐exposed pregnancy preventionAmerican Indian and Alaska nativeCHOICEScontraception

Identifiers

PMID39710495
PMCPMC11828969

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.