Evidence map›Paper›PMID 39710009›Full record

ArticleMagnetic resonance imaging2025

Combination of deep learning reconstruction and quantification for dynamic contrast-enhanced (DCE) MRI.

Juntong Jing, Anthony Mekhanik, Melanie Schellenberg, Victor Murray, Ouri Cohen, Ricardo Otazo

Abstract read
In one paragraph

Article in Magnetic resonance imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juntong JingWeill Cornell Graduate School of Medical Sciences, New York, NY, United States.
Anthony MekhanikDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Melanie SchellenbergDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Victor MurrayDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Ouri CohenDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Ricardo OtazoWeill Cornell Graduate School of Medical Sciences, New York, NY, United States; Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States; Department of Radiology, Memorial Sloan Kettering Cancer Center, NY, New York, USA. Electronic address: otazotoj@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Development of a Clinical CEST MR Fingerprinting Method for Treatment Response Assessment in Brain MetastasesR37CA262662 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Ouri Cohen · 2022 to 2026
$3.4M
Rapid motion-robust quantitative DCE-MRI for the assessment of gynecologic cancersR01CA244532 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI AKIN, OGUZ, OTAZO, RICARDO · 2020 to 2024
$2.9M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA244532NCI NIH HHS R37 CA262662
6 · The paper itself

Abstract

Dynamic contrast-enhanced (DCE) MRI is an important imaging tool for evaluating tumor vascularity that can lead to improved characterization of tumor extent and heterogeneity, and for early assessment of treatment response. However, clinical adoption of quantitative DCE-MRI remains limited due to challenges in acquisition and quantification performance, and lack of automated tools. This study presents an end-to-end deep learning pipeline that exploits a novel deep reconstruction network called DCE-Movienet with a previously developed deep quantification network called DCE-Qnet for fast and quantitative DCE-MRI. DCE-Movienet offers rapid reconstruction of high spatiotemporal resolution 4D MRI data, reducing reconstruction time of the full acquisition to only 0.66 s, which is significantly shorter than compressed sensing's order of 10 min-long reconstructions, without affecting image quality. DCE-Qnet can then perform comprehensive quantification of perfusion parameter maps (K

Indexed as

Contrast MediaDeep LearningImage Processing, Computer-AssistedMagnetic Resonance ImagingAlgorithmsFemaleHumansImage Interpretation, Computer-AssistedContrast MediaDCE-MRIDCE-MRI quantificationDCE-MRI reconstructionDeep learning

Identifiers

PMID39710009
PMCPMC12224515

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.