ArticleUltrasonics sonochemistry2025
Extraction of American ginseng polysaccharide by ultrasound-assisted deep eutectic solvents-based three-phase partitioning: Process optimization, structural characterization, and anti-ulcerative colitis study.
Article in Ultrasonics sonochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed.
- Review
- Natural polysaccharides targeting mitochondrial function for colorectal cancer prevention and treatment: mechanisms and nano-delivery strategies.Chinese medicine · 2026Review
- Ultrasonic-assisted ternary deep eutectic solvent extraction of polysaccharides from fermented black beans (Dan-Dou-Chi): structural features, antioxidant, and hypoglycemic activities.Food chemistry: X · 2026Article
- Ultrasound-Assisted Deep Eutectic Solvent Three-Phase Partitioning System for Extraction of Polysaccharides from Longan Shell: Process Optimization, Physicochemical Properties, Structural Characterization, and Antioxidant Activities.Foods (Basel, Switzerland) · 2026Article
- Ultrasound-assisted aqueous two-phase extraction of flavonoids from erigeron breviscapus: process optimization, structural characterization, antioxidant study, and DFT calculation.Scientific reports · 2026Article
- Ultrasound-Assisted Extraction, Macroporous Resin Purification, and Antioxidant Activity of Chlorogenic Acid fromFoods (Basel, Switzerland) · 2026Article
- Recent Progressions in Applications of Bioactive Polysaccharides in Food and Health Sciences: A Comprehensive Review.Food science & nutrition · 2026Review
- Research advances in red ginseng polysaccharides: preparation, structural characteristics and immunomodulatory effect.Frontiers in pharmacology · 2026Review
- Extraction ofMolecules (Basel, Switzerland) · 2025Article
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12 authors.
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Abstract
Three-phase partitioning (TPP) is promising for isolating bioactive polysaccharides, but t-butanol's environmental impact limits its application. Deep eutectic solvents can serve as a green and recyclable alternative to t-butanol. This study introduces an ultrasonic-assisted DES three-phase partitioning (UA-TPP-DES) system to extract and purify American ginseng polysaccharides (AGPs). The optimized DES-4, composed of lauric acid and nonanoic acid (molar ratio = 1:1), achieved a 35.28 % extraction yield under specific conditions and can be recycled five times with minimal yield loss. AGP-DES-4 has a broad molecular weight distribution (2.48-174.64 kDa) and mainly consists of mannose, glucose, galactose, and arabinose. In vivo Drosophila models show that AGP-DES-4 improves UC fly survival and enhances intestinal barrier function by regulating the proliferation and differentiation of intestinal epithelial cells (IECs) and intestinal stem cells (ISCs). Our results highlight the effectiveness of the AGP-DES-4 extraction method and its potential therapeutic value for treating UC.
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