Evidence map›Paper›PMID 39709409›Full record

ArticleBMC palliative care2024

Decision-making about palliative sedation for patients with cancer: a qualitative study in five European countries linked to the Palliative sedation project.

Michael Van der Elst, Sheila Payne, Maria Arantzamendi, Nancy N Preston, Ian Koper, Alazne Belar, Holger Brunsch, Séverine M Surges, Claudio Adile, Yasmine Grassi and 4 more

Abstract read
In one paragraph

Article in BMC palliative care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Michael Van der ElstDepartment of Oncology, Laboratory of Experimental Radiotherapy, Katholieke Universiteit Leuven, Herestraat 49, 3000, Louvain, Belgium.ORCID http://orcid.org/0000-0001-9381-7287
Sheila PayneInternational Observatory On End of Life Care, Faculty of Health and Medicine, Lancaster University, Lancaster, LA1 4AT, UK. s.a.payne@lancaster.ac.uk.ORCID http://orcid.org/0000-0001-6982-9181
Maria ArantzamendiInstitute for Culture and Society-ATLANTES, Universidad de Navarra, Calle Universidad, 6, 31009, Pamplona, Navarra, Spain.ORCID http://orcid.org/0000-0003-2406-0668
Nancy N PrestonInternational Observatory On End of Life Care, Faculty of Health and Medicine, Lancaster University, Lancaster, LA1 4AT, UK.ORCID http://orcid.org/0000-0003-2659-2342
Ian KoperDepartment of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Centre, Geert Grooteplein 10, 6500 HB, Nijmegen, Netherlands.ORCID http://orcid.org/0000-0001-6593-4822
Alazne BelarInstitute for Culture and Society-ATLANTES, Universidad de Navarra, Calle Universidad, 6, 31009, Pamplona, Navarra, Spain.ORCID http://orcid.org/0000-0002-4831-5218
Holger BrunschDepartment of Palliative Medicine, University Hospital Bonn, Venusberg Campus 1, 53127, Bonn, Germany.
Séverine M SurgesDepartment of Palliative Medicine, University Hospital Bonn, Venusberg Campus 1, 53127, Bonn, Germany.ORCID http://orcid.org/0000-0001-6991-1767
Claudio AdileLa Maddalena Cancer Center, Via San Lorenzo 312, 90146, Palermo, Italy.ORCID http://orcid.org/0000-0002-0664-3520
Yasmine GrassiLa Maddalena Cancer Center, Via San Lorenzo 312, 90146, Palermo, Italy.ORCID http://orcid.org/0000-0002-2060-0420
Zoe CockshottInternational Observatory On End of Life Care, Faculty of Health and Medicine, Lancaster University, Lancaster, LA1 4AT, UK.ORCID http://orcid.org/0000-0003-2041-609X
Jeroen HasselaarDepartment of Primary and Community Care, Radboud University Medical Centre, Geert Grooteplein 10, 6500 HB, Nijmegen, Netherlands.ORCID http://orcid.org/0000-0002-8880-2029
Johan MentenDepartment of Oncology, Laboratory of Experimental Radiotherapy, Katholieke Universiteit Leuven, Herestraat 49, 3000, Louvain, Belgium.ORCID http://orcid.org/0000-0003-2805-1953
Palliative Sedation Consortium

Funding

Horizon 2020 Framework Program of the European Union 825700
6 · The paper itself

Abstract

backgroundPalliative sedation refers to the proportional use of titrated medication which reduces consciousness with the aim of relieving refractory suffering related to physical and psychological symptoms and/or existential distress near the end of life. Palliative sedation is intended to be an end of life option that enables healthcare professionals to provide good patient care but there remains controversy on how it is used. Little is known about decision-making processes regarding this procedure. The aim of this study was to explore decision-making processes in palliative sedation based on the experiences and perceptions of relatives and healthcare professionals.

methodsWe conducted a qualitative interview study with dyads (a bereaved relative and a healthcare professional) linked to 33 deceased patient with cancer who had palliative sedation, in seven in-patient palliative care settings in five countries (Belgium, Germany, Italy, the Netherlands, and Spain). A framework analysis approach was used to analyse the data.

resultsTwo main themes are defined: 1) Decision-making about palliative sedation is a complex iterative process, 2) Decision-making is a shared process between the patient, healthcare professionals, and relatives. Decision-making about palliative sedation appears to follow an iterative process of shared information, deliberation, and decision-making. The patient and healthcare professionals are the main stakeholders, but relatives are involved and may advocate for, or delay, the decision-making process. Starting palliative sedation is reported to be an emotionally difficult decision for all parties.

conclusionsAs decision-making about palliative sedation is a complex and iterative process, patients, relatives and healthcare professionals need time for regular discussions. This requires a high level of engagement by healthcare professionals, that takes into account patients' wishes and needs, and helps to facilitate decision-making.

Indexed as

Decision MakingNeoplasmsPalliative CareQualitative ResearchAdultAgedAged, 80 and overBelgiumEuropeFemaleGermanyHumansHypnotics and SedativesItalyMaleMiddle AgedHypnotics and SedativesCancerDecision-makingEuropeHealth personnelPalliative CarePalliative SedationQualitative research

Identifiers

PMID39709409
PMCPMC11662527

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.