ReviewJournal of advanced research2025
The role of trehalose metabolism in plant stress tolerance.
Review in Journal of advanced research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- The effect and mechanism of melatonin-trehalose-selenium nanoparticles in alleviating the phytotoxicity of butachlor in rice.Pest management science · 2026Article
- Volatile and non-volatile organic compounds synergistically determine quality inFood chemistry: X · 2026Article
- Duet between sugars and hormones: The molecular dialogue fine-tuning hypoxia acclimation in plants.Journal of integrative plant biology · 2026Review
- Responses, Physiological and Molecular Mechanisms, and Mitigation Strategies of Grapevine Under Salt Stress.International journal of molecular sciences · 2026Review
- Integrated physiological, transcriptomic, and metabolomic analysis of exogenous trehalose regulating cold tolerance in grape callus.BMC plant biology · 2026Article
- Glutathione peroxidase gene regulates heat stress response via trehalose synthesis in Pleurotus ostreatus.Applied microbiology and biotechnology · 2026Article
- Integrated physiological and transcriptomic measurements reveal changes in the accumulation and partitioning of storage reserves after prevention of pollination in maize.BMC plant biology · 2026Article
- Gas-Assisted Steam Explosion Enables Targeted Regulation of Nutritional and Flavor Quality inFoods (Basel, Switzerland) · 2026Article
- Integrated Multi-Omics Characterization of the Salt-Sensitive MutantPlants (Basel, Switzerland) · 2026Article
- Exometabolomic-enabled discovery of compounds associated with Escherichia coli O157:H7 population dynamics in the lettuce phyllosphere.BMC plant biology · 2026Article
- Trehalose: a multifunctional sugar and its metabolites are biotechnological targets for crop salinity tolerance under saline conditions.Plant molecular biology · 2026Review
- Salicylic Acid Enhances Cadmium Tolerance inPlants (Basel, Switzerland) · 2026Article
- Genomic Analysis of the Trehalose-6-Phosphate Synthase Family Involved in Trehalose Biosynthesis and Drought Response inCurrent issues in molecular biology · 2026Article
- Pan-genomic analysis and abiotic stress expression of eight TPS gene families in Brassica napus.BMC plant biology · 2026Article
- From Shared Mechanisms to Precision Breeding: Engineering Cold and Drought Cross-Tolerance in Crops.International journal of molecular sciences · 2026Review
- Article
- Systematic perturbation of cultures of K. phaffii by carbon co-feeding show gene signatures associated with production of recombinant proteins.Microbial cell factories · 2026Article
- PpZAT12 from a native Kentucky bluegrass (Poa pratensis L.) confers drought tolerance through regulating antioxidant defense system and multiple metabolic pathways.BMC plant biology · 2026Article
- Dose-response-defined physiological framework enables comparative analysis of transcriptional response dynamics across multiple herbicides inFrontiers in plant science · 2026Article
- Identification of early metabolic indicator candidates in scion leaves associated with delayed incompatibility in tomato and pepper grafting via metabolism.Frontiers in plant science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrehalose is a nonreducing disaccharide containing two glucose molecules linked through an α,α-1,1-glycosidic bond. This unique chemical structure causes trehalose levels to fluctuate significantly in plants under stress, where it functions as an osmoprotectant, enhancing plant resistance to stress. Previous studies have confirmed that the trehalose synthesis pathway is widely conserved across most plants. However, the protective role of trehalose is limited only to organelles or tissues where the concentration is sufficiently high. AIM OF REVIEW: In this review, we summarize previous reports on improving plant stress tolerance (drought, cold, heat, salt, pathogen, etc.) by applying trehalose-6-phosphate (T6P) or trehalose and manipulating the expression of trehalose metabolism-related genes. The molecular mechanisms underlying T6P, trehalose, and their related genes that regulate plant stress resistance are reviewed. More progressive studies on the spatiotemporal control of trehalose metabolism will provide a novel tool that allows for the simultaneous enhancement of crop yield and stress tolerance. KEY SCIENTIFIC CONCEPTS OF REVIEW: We introduce the history of trehalose and discuss the possibility of trehalose and its metabolity-related genes binding to T6P to participate in stress response through unknown signaling pathways. In addition, the effects of trehalose metabolism regulation on plant growth and stress resistance were reviewed, and the molecular mechanism was fully discussed. In particular, we came up with new insights that the molecular mechanism of trehalose metabolism to enhance plant stress resistance in the future and we propose the need to use biotechnology methods to cultivate crops with stress resistance and high yield potential.
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Registered trials
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