SynthesisVeterinary medicine and science2025
Effects of Amino Acid Supplementation on the Growth Performance of Broiler Chicks Challenged With Coccidiosis: A Meta-Analysis.
Synthesis in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- Histidine requirement of broilers in a necrotic enteritis challenge model: Growth performance and carcass parameters.Poultry science · 2026Article
- Nutritional strategies to mitigate sub-clinical coccidiosis in Eimeria-challenged broilers.Poultry science · 2026Article
- Functional Amino Acid Supplementation Drives Early Growth and Gut Maturation in Broilers: A Meta-Analysis.Animals : an open access journal from MDPI · 2026Review
- Insights into Non-Antibiotic Alternative and Emerging Control Strategies for Chicken Coccidiosis.Animals : an open access journal from MDPI · 2026Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This meta-analysis aimed to evaluate the effects of amino acid supplementation on the growth performance of broiler chicks challenged with coccidiosis. Data were collected on authorship, publication year, study sample characteristics and outcomes of interest related to growth performance. Effect sizes were calculated for both overall effects and the individual effects of each amino acid. The effects of moderator factors, such as supplementation levels and duration, were also assessed, and bias was calculated. Works were obtained from PubMed, Elsevier, ScienceDirect, Wiley, Springer Link and Scopus databases, with the help of search engines like Google Scholar and ResearchGate, covering the period from 2013 to 2023. A random-effects model was used. Thirteen works were included in the current analysis, examining the effects of arginine (n = 4), methionine (n = 6), threonine (n = 3) and glutamine (n = 3). Amino acid supplementation [0.326, CI 95% (0.297-0.355); p = 0.000], arginine [0.430, CI 95% (0.293-0.568); p = 0.000] and threonine [0.793, CI 95% (0.193-1.38); p = 0.009] significantly increased body weight. Amino acid supplementation [0.052, CI 95% (0.022-0.081); p = 0.000] and arginine [0.317, CI 95% (0.049-0.585); p = 0.000] also significantly increased feed intake. Higher levels of amino acids (≥1.50%) and longer supplementation periods (≥15 days) significantly increased body weight and feed intake, while reducing the feed conversion ratio. Funnel plots, fail-safe N and Egger tests showed no evidence of bias. In conclusion, arginine supplementation has the potential to increase body weight and feed intake in poultry challenged with coccidiosis. Higher doses of amino acids and longer supplementation periods are recommended in such cases.
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