Evidence map›Paper›PMID 39708194›Full record

ArticleInternational urology and nephrology2025

The effects of microsurgical varicocelectomy performed for infertility on premature ejaculation.

Yalcin Kizilkan, Mesut Berkan Duran, Mehmet Vehbi Kayra, Bahadir Sahin, Serdar Toksoz, Mehmet Hamza Gultekin, Omer Yildirim, Murat Gul, Nebil Akdogan, Kagan Turker Akbaba and 11 more

Abstract readMulticenter Study
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In one paragraph

Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Yalcin KizilkanAnkara City Hospital, Ankara, Turkey. yalcinkizilkan@yahoo.com.
Mesut Berkan DuranPamukkale University School of Medicine, Denizli, Turkey.
Mehmet Vehbi KayraBaskent University Faculty of Medicine, Adana Dr. Turgut Noyan Application and Research Center, Adana, Turkey.
Bahadir SahinMarmara University Training and Research Hospital, Istanbul, Turkey.
Serdar ToksozSincan Training and Research Hospital, Ankara, Turkey.
Mehmet Hamza GultekinIstanbul University, Istanbul, Turkey.
Omer YildirimGelibolu State Hospital, Canakkale, Turkey.
Murat GulSelcuk University, Konya, Turkey.
Nebil AkdoganCukurova University, Adana, Turkey.
Kagan Turker AkbabaIzmir City Hospital, Izmir, Turkey.
Iyimser UreEskisehir Osmangazi University, Eskisehir, Turkey.
Eray HasirciBaskent University, Ankara, Turkey.
Oguzhan KahramanBaskent University, Konya Training and Research Hospital, Konya, Turkey.
Erman CeyhanBaskent University, Ankara, Turkey.
Abdulmecit YavuzIstinye University, Istanbul, Turkey.
Ugur AkgunBursa City Hospital, Bursa, Turkey.
Onder CinarMedicana Hospital, Samsun, Turkey.
Umit GulTarsus MMT Hospital, Mersin, Turkey.
Hasan DeliktasMugla University, Mugla, Turkey.
Hamdi OzkaraIstanbul University, Istanbul, Turkey.
Tahsin TuruncUrocentre Urology Clinic, Adana, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effects of varicocelectomy on premature ejaculation (PE) in patients with varicocele and infertility.

methodsA total of 82 sexually active patients aged 18 years or over who had undergone microscopic subinguinal varicocelectomy with a clinical diagnosis of varicocele in 14 urology clinics between October 2021 and March 2023 with primary infertility were evaluated prospectively Patients were evaluated using the Turkish validated form of the 'Premature Ejaculation Diagnostic Tool' (PEDT) scale. A PEDT score of 11 or above was taken to indicate the presence of PE. Turkish validated forms of PEDT and International Index of Erectile Function-5 (IIEF-5) were completed in all patients pre-operatively and at 3 and 6 months post-operatively. Intravaginal ejaculatory latency time (IELT) and serum testosterone measurements were also recorded.

resultsLeft varicocelectomy was performed in 70.7% and bilateral varicocelectomy in 29.3% of the participants. A significant difference was found between pre- and post-operative PEDT scores (× 2 (2) = 130.1, p < 0.001). A significant difference was observed between pre- and post-operative IELT time (× 2 (2) = 143.2, p < 0.001). IIEF-5 scores differed before and after surgery (× 2 (2) = 59.5, p < 0.001). A difference was found between the testosterone levels measured before and after surgery (× 2 (2) = 40.9, p < 0.001). No statistically significant difference was observed between the third- and sixth-month testosterone values (p = 0.183). Testosterone levels (p = 0.001) and IELT scores (p < 0.001) were significantly higher, while PEDT scores (p < 0.001) were significantly lower in the bilateral varicocelectomy group at the sixth post-operative month.

conclusionIn light of our findings, it is recommended that infertile patients with varicocele be informed of the positive effects of varicocelectomy on PE.

Indexed as

Infertility, MaleMicrosurgeryPremature EjaculationUrologic Surgical Procedures, MaleVaricoceleAdultHumansMaleProspective StudiesTestosteroneYoung AdultTestosteroneErectionInfertilityPremature ejaculationVaricocelectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.