ArticleArchives of orthopaedic and trauma surgery2024
What are the risk factors and microorganism profiles of periprosthetic hip joint infections with a concomitant sinus tract?
Article in Archives of orthopaedic and trauma surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Differentiating Normal Healing From Infection in Total Joint Arthroplasty: An Educational and Diagnostic Tool for Emergency Providers Evaluating the Postoperative Patient.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026Review
- Sinus tract and purulence as clinical criteria for periprosthetic joint infection: diagnostic accuracy, microorganisms, and clinical outcomes.Journal of bone and joint infection · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionA sinus tract, an abnormal channel between the skin and joint, is a major criterion that proves the presence of an underlying periprosthetic joint infection. Its presence not only increases failure rates but also leads to poor outcomes. Despite its clinical relevance, little is known about risk factors and underlying microorganism profiles. The aim of this study was to investigate PJIs of the hip with a sinus tract, identifying risk factors and microorganism profiles. MATERIALS AND
methodsThis was a retrospective case control study of all PJI cases of the hip treated at our institution. A total of 4,368 cases with a PJI of the hip were identified of which 653 patients (14.95%), displayed a sinus tract. Univariate and multivariate analysis was performed. Odds ratio (OR) and 95% confidence interval (CI) were presented.
resultsMultivariate analysis identified diabetes mellitus (p = 0.004; OR = 1.62; 95% CI 1.17-2.44), history of ileus (p < 0.001; OR = 4.65; 95% CI 2.38-9.08), osteomyelitis (p < 0.001; OR = 2.35; 95% CI 1.65-3.35) and prior revisions (p = 0-014; OR = 1.36; 95% CI 1.07-1.74) as risk factors for a sinus tract. Polymicrobial infections (p < 0.001; OR = 2.35; 95% CI 1.86-2.96), Staphylococcus aureus (p < 0.001; OR = 3.67; 95% CI 2.86-4.71) and Escherichia coli (p = 0.014; OR = 1.65; 95% CI 1.11-2.46) were associated with a sinus tract in PJIs of the hip.
conclusionsMicroorganism profiles and risk factors differ significantly in patients with PJI of a THA with a sinus tract. These insights can help surgeons in planning and selecting appropriate antibiotics for cement loading and empiric antibiotic treatment, as well as in risk stratification of patients, who may develop a sinus tract following THA.
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